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The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma.
Heider M, Eichner R, Stroh J, Morath V, Kuisl A, Zecha J, Lawatscheck J, Baek K, Garz AK, Rudelius M, Deuschle FC, Keller U, Lemeer S, Verbeek M, Götze KS, Skerra A, Weber WA, Buchner J, Schulman BA, Kuster B, Fernández-Sáiz V, Bassermann F. Heider M, et al. Among authors: skerra a. Mol Cell. 2021 Mar 18;81(6):1170-1186.e10. doi: 10.1016/j.molcel.2020.12.046. Epub 2021 Feb 10. Mol Cell. 2021. PMID: 33571422 Free PMC article.
Design and characterization of a modular membrane protein anchor to functionalize the moss Physcomitrella patens with extracellular catalytic and/or binding activities.
Morath V, Truong DJ, Albrecht F, Polte I, Ciccone RA, Funke LF, Reichart L, Wolf CG, Brunner AD, Fischer K, Schneider PC, Brüggenthies JB, Fröhlich F, Wiedemann G, Reski R, Skerra A. Morath V, et al. Among authors: skerra a. ACS Synth Biol. 2014 Dec 19;3(12):990-4. doi: 10.1021/sb5000302. ACS Synth Biol. 2014. PMID: 25524107
Treatment of diet-induced lipodystrophic C57BL/6J mice with long-acting PASylated leptin normalises insulin sensitivity and hepatic steatosis by promoting lipid utilisation.
Bolze F, Bast A, Mocek S, Morath V, Yuan D, Rink N, Schlapschy M, Zimmermann A, Heikenwalder M, Skerra A, Klingenspor M. Bolze F, et al. Among authors: skerra a. Diabetologia. 2016 Sep;59(9):2005-12. doi: 10.1007/s00125-016-4004-6. Epub 2016 Jun 7. Diabetologia. 2016. PMID: 27272237
243 results