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Skin sensitisation: the Colipa strategy for developing and evaluating non-animal test methods for risk assessment.
Maxwell G, Aeby P, Ashikaga T, Bessou-Touya S, Diembeck W, Gerberick F, Kern P, Marrec-Fairley M, Ovigne JM, Sakaguchi H, Schroeder K, Tailhardat M, Teissier S, Winkler P. Maxwell G, et al. ALTEX. 2011;28(1):50-5. doi: 10.14573/altex.2011.1.050. ALTEX. 2011. PMID: 21311850 Free article.
At present three non-animal test methods (Direct Peptide Reactivity Assay (DPRA), Myeloid U937 Skin Sensitisation Test (MUSST) and human Cell Line Activation Test (hCLAT)) have been evaluated in Colipa interlab …
At present three non-animal test methods (Direct Peptide Reactivity Assay (DPRA), Myeloid U937 Skin Se
Guiding principles for the implementation of non-animal safety assessment approaches for cosmetics: skin sensitisation.
Goebel C, Aeby P, Ade N, Alépée N, Aptula A, Araki D, Dufour E, Gilmour N, Hibatallah J, Keller D, Kern P, Kirst A, Marrec-Fairley M, Maxwell G, Rowland J, Safford B, Schellauf F, Schepky A, Seaman C, Teichert T, Tessier N, Teissier S, Weltzien HU, Winkler P, Scheel J. Goebel C, et al. Regul Toxicol Pharmacol. 2012 Jun;63(1):40-52. doi: 10.1016/j.yrtph.2012.02.007. Epub 2012 Feb 21. Regul Toxicol Pharmacol. 2012. PMID: 22374415 Free article.
At present the mouse local lymph node assay (LLNA) remains the 'gold standard' test method for this purpose however non-animal test methods are under development that aim to replace the need for new animal test data. …
At present the mouse local lymph node assay (LLNA) remains the 'gold standard' test method for this purpose however non