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Page 1
Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases.
Jurczyluk J, Munoz MA, Skinner OP, Chai RC, Ali N, Palendira U, Quinn JM, Preston A, Tangye SG, Brown AJ, Argent E, Ziegler JB, Mehr S, Rogers MJ. Jurczyluk J, et al. Among authors: skinner op. Immunol Cell Biol. 2016 Nov;94(10):994-999. doi: 10.1038/icb.2016.58. Epub 2016 Jul 5. Immunol Cell Biol. 2016. PMID: 27377765 Free PMC article.
Lack of protein prenylation promotes NLRP3 inflammasome assembly in human monocytes.
Skinner OP, Jurczyluk J, Baker PJ, Masters SL, Rios Wilks AG, Clearwater MS, Robertson AAB, Schroder K, Mehr S, Munoz MA, Rogers MJ. Skinner OP, et al. J Allergy Clin Immunol. 2019 Jun;143(6):2315-2317.e3. doi: 10.1016/j.jaci.2019.02.013. Epub 2019 Feb 21. J Allergy Clin Immunol. 2019. PMID: 30797829 Free article. No abstract available.
Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency.
Munoz MA, Skinner OP, Masle-Farquhar E, Jurczyluk J, Xiao Y, Fletcher EK, Kristianto E, Hodson MP, O'Donoghue SI, Kaur S, Brink R, Zahra DG, Deenick EK, Perry KA, Robertson AA, Mehr S, Hissaria P, Mulders-Manders CM, Simon A, Rogers MJ. Munoz MA, et al. Among authors: skinner op. J Clin Invest. 2022 Oct 3;132(19):e160929. doi: 10.1172/JCI160929. J Clin Invest. 2022. PMID: 36189795 Free PMC article.
Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity.
Ryan KA, Bewley KR, Fotheringham SA, Slack GS, Brown P, Hall Y, Wand NI, Marriott AC, Cavell BE, Tree JA, Allen L, Aram MJ, Bean TJ, Brunt E, Buttigieg KR, Carter DP, Cobb R, Coombes NS, Findlay-Wilson SJ, Godwin KJ, Gooch KE, Gouriet J, Halkerston R, Harris DJ, Hender TH, Humphries HE, Hunter L, Ho CMK, Kennard CL, Leung S, Longet S, Ngabo D, Osman KL, Paterson J, Penn EJ, Pullan ST, Rayner E, Skinner O, Steeds K, Taylor I, Tipton T, Thomas S, Turner C, Watson RJ, Wiblin NR, Charlton S, Hallis B, Hiscox JA, Funnell S, Dennis MJ, Whittaker CJ, Catton MG, Druce J, Salguero FJ, Carroll MW. Ryan KA, et al. Nat Commun. 2021 Jan 4;12(1):81. doi: 10.1038/s41467-020-20439-y. Nat Commun. 2021. PMID: 33398055 Free PMC article.
Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites.
Lansink LIM, Skinner OP, Engel JA, Lee HJ, Soon MSF, Williams CG, SheelaNair A, Pernold CPS, Laohamonthonkul P, Akter J, Stoll T, Hill MM, Talman AM, Russell A, Lawniczak M, Jia X, Chua B, Anderson D, Creek DJ, Davenport MP, Khoury DS, Haque A. Lansink LIM, et al. Among authors: skinner op. mBio. 2023 Aug 31;14(4):e0112923. doi: 10.1128/mbio.01129-23. Epub 2023 Jul 14. mBio. 2023. PMID: 37449844 Free PMC article.