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Inhibition of beta-catenin translocation in rodent colorectal tumors: a novel explanation for the protective effect of nonsteroidal antiinflammatory drugs in colorectal cancer.
Brown WA, Skinner SA, Vogiagis D, O'Brien PE. Brown WA, et al. Among authors: skinner sa. Dig Dis Sci. 2001 Nov;46(11):2314-21. doi: 10.1023/a:1012326525692. Dig Dis Sci. 2001. PMID: 11713928
5-aminosalicyclic acid and olsalazine inhibit tumor growth in a rodent model of colorectal cancer.
Brown WA, Farmer KC, Skinner SA, Malcontenti-Wilson C, Misajon A, O'Brien PE. Brown WA, et al. Among authors: skinner sa. Dig Dis Sci. 2000 Aug;45(8):1578-84. doi: 10.1023/a:1005517112039. Dig Dis Sci. 2000. PMID: 11007109
Inhibition of rat colon tumors by sulindac and sulindac sulfone is independent of K-ras (codon 12) mutation.
de Jong TA, Skinner SA, Malcontenti-Wilson C, Vogiagis D, Bailey M, van Driel IR, O'Brien PE. de Jong TA, et al. Among authors: skinner sa. Am J Physiol Gastrointest Liver Physiol. 2000 Feb;278(2):G266-72. doi: 10.1152/ajpgi.2000.278.2.G266. Am J Physiol Gastrointest Liver Physiol. 2000. PMID: 10666051
Sulindac inhibits colorectal tumour growth, but not prostaglandin synthesis in the rat.
Charalambous D, Skinner SA, O'Brien PE. Charalambous D, et al. Among authors: skinner sa. J Gastroenterol Hepatol. 1998 Dec;13(12):1195-200. J Gastroenterol Hepatol. 1998. PMID: 9918425
Microvascular structure of benign and malignant tumors of the colon in humans.
Skinner SA, Frydman GM, O'Brien PE. Skinner SA, et al. Dig Dis Sci. 1995 Feb;40(2):373-84. doi: 10.1007/BF02065424. Dig Dis Sci. 1995. PMID: 7851202
Sulindac inhibits the rate of growth and appearance of colon tumors in the rat.
Skinner SA, Penney AG, O'Brien PE. Skinner SA, et al. Arch Surg. 1991 Sep;126(9):1094-6. doi: 10.1001/archsurg.1991.01410330048007. Arch Surg. 1991. PMID: 1929839
Microvascular architecture of experimental colon tumors in the rat.
Skinner SA, Tutton PJ, O'Brien PE. Skinner SA, et al. Cancer Res. 1990 Apr 15;50(8):2411-7. Cancer Res. 1990. PMID: 2317825
Non-steroidal anti-inflammatory drugs with different cyclooxygenase inhibitory profiles that prevent aberrant crypt foci formation but vary in acute gastrotoxicity in a rat model.
Brown WA, Skinner SA, Malcontenti-Wilson C, Misajon A, DeJong T, Vogiagis D, O'Brien PE. Brown WA, et al. Among authors: skinner sa. J Gastroenterol Hepatol. 2000 Dec;15(12):1386-92. doi: 10.1046/j.1440-1746.2000.02370.x. J Gastroenterol Hepatol. 2000. PMID: 11197048
Non-steroidal anti-inflammatory drugs with activity against either cyclooxygenase 1 or cyclooxygenase 2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation.
Brown WA, Skinner SA, Malcontenti-Wilson C, Vogiagis D, O'Brien PE. Brown WA, et al. Among authors: skinner sa. Gut. 2001 May;48(5):660-6. doi: 10.1136/gut.48.5.660. Gut. 2001. PMID: 11302965 Free PMC article.
A prospective, randomized, controlled clinical trial of placement of the artificial bowel sphincter (Acticon Neosphincter) for the control of fecal incontinence.
O'Brien PE, Dixon JB, Skinner S, Laurie C, Khera A, Fonda D. O'Brien PE, et al. Among authors: skinner s. Dis Colon Rectum. 2004 Nov;47(11):1852-60. doi: 10.1007/s10350-004-0717-6. Dis Colon Rectum. 2004. PMID: 15622577 Clinical Trial.
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