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In vivo effects of a GPR30 antagonist.
Dennis MK, Burai R, Ramesh C, Petrie WK, Alcon SN, Nayak TK, Bologa CG, Leitao A, Brailoiu E, Deliu E, Dun NJ, Sklar LA, Hathaway HJ, Arterburn JB, Oprea TI, Prossnitz ER. Dennis MK, et al. Among authors: sklar la. Nat Chem Biol. 2009 Jun;5(6):421-7. doi: 10.1038/nchembio.168. Nat Chem Biol. 2009. PMID: 19430488 Free PMC article.
Virtual and biomolecular screening converge on a selective agonist for GPR30.
Bologa CG, Revankar CM, Young SM, Edwards BS, Arterburn JB, Kiselyov AS, Parker MA, Tkachenko SE, Savchuck NP, Sklar LA, Oprea TI, Prossnitz ER. Bologa CG, et al. Among authors: sklar la. Nat Chem Biol. 2006 Apr;2(4):207-12. doi: 10.1038/nchembio775. Epub 2006 Mar 5. Nat Chem Biol. 2006. PMID: 16520733
Linkage effects on binding affinity and activation of GPR30 and estrogen receptors ERalpha/beta with tridentate pyridin-2-yl hydrazine tricarbonyl-Re/(99m)Tc(I) chelates.
Ramesh C, Bryant B, Nayak T, Revankar CM, Anderson T, Carlson KE, Katzenellenbogen JA, Sklar LA, Norenberg JP, Prossnitz ER, Arterburn JB. Ramesh C, et al. Among authors: sklar la. J Am Chem Soc. 2006 Nov 15;128(45):14476-7. doi: 10.1021/ja066360p. J Am Chem Soc. 2006. PMID: 17090028 Free PMC article.
GPR30: A G protein-coupled receptor for estrogen.
Prossnitz ER, Arterburn JB, Sklar LA. Prossnitz ER, et al. Among authors: sklar la. Mol Cell Endocrinol. 2007 Feb;265-266:138-42. doi: 10.1016/j.mce.2006.12.010. Epub 2007 Jan 11. Mol Cell Endocrinol. 2007. PMID: 17222505 Free PMC article. Review.
GPR30: a novel therapeutic target in estrogen-related disease.
Prossnitz ER, Sklar LA, Oprea TI, Arterburn JB. Prossnitz ER, et al. Among authors: sklar la. Trends Pharmacol Sci. 2008 Mar;29(3):116-23. doi: 10.1016/j.tips.2008.01.001. Epub 2008 Feb 11. Trends Pharmacol Sci. 2008. PMID: 18262661
The ins and outs of GPR30: a transmembrane estrogen receptor.
Prossnitz ER, Oprea TI, Sklar LA, Arterburn JB. Prossnitz ER, et al. Among authors: sklar la. J Steroid Biochem Mol Biol. 2008 Apr;109(3-5):350-3. doi: 10.1016/j.jsbmb.2008.03.006. Epub 2008 Mar 6. J Steroid Biochem Mol Biol. 2008. PMID: 18406603 Free PMC article. Review.
340 results