Sklar LA - Search Results

1

Functional and clinical relevance of VLA-4 (CD49d/CD29) in ibrutinib-treated chronic lymphocytic leukemia.

Tissino E, Benedetti D, Herman SEM, Ten Hacken E, Ahn IE, Chaffee KG, Rossi FM, Dal Bo M, Bulian P, Bomben R, Bayer E, Härzschel A, Gutjahr JC, Postorino M, Santinelli E, Ayed A, Zaja F, Chiarenza A, Pozzato G, Chigaev A, Sklar LA, Burger JA, Ferrajoli A, Shanafelt TD, Wiestner A, Del Poeta G, Hartmann TN, Gattei V, Zucchetto A. Tissino E, et al. Among authors: sklar la. J Exp Med. 2018 Feb 5;215(2):681-697. doi: 10.1084/jem.20171288. Epub 2018 Jan 4. J Exp Med. 2018. PMID: 29301866 Free PMC article.

2

Aspects of VLA-4 and LFA-1 regulation that may contribute to rolling and firm adhesion.

Chigaev A, Sklar LA. Chigaev A, et al. Among authors: sklar la. Front Immunol. 2012 Aug 2;3:242. doi: 10.3389/fimmu.2012.00242. eCollection 2012. Front Immunol. 2012. PMID: 22876249 Free PMC article.

3

Regulation of cell adhesion by affinity and conformational unbending of alpha4beta1 integrin.

Chigaev A, Waller A, Zwartz GJ, Buranda T, Sklar LA. Chigaev A, et al. Among authors: sklar la. J Immunol. 2007 Jun 1;178(11):6828-39. doi: 10.4049/jimmunol.178.11.6828. J Immunol. 2007. PMID: 17513731

4

Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion.

Chigaev A, Smagley Y, Sklar LA. Chigaev A, et al. Among authors: sklar la. BMC Immunol. 2011 May 17;12:28. doi: 10.1186/1471-2172-12-28. BMC Immunol. 2011. PMID: 21586157 Free PMC article.

5

Overview: assays for studying integrin-dependent cell adhesion.

Chigaev A, Sklar LA. Chigaev A, et al. Among authors: sklar la. Methods Mol Biol. 2012;757:3-14. doi: 10.1007/978-1-61779-166-6_1. Methods Mol Biol. 2012. PMID: 21909902 Free PMC article. Review.

6

Is prolonged stem cell mobilization detrimental for hematopoiesis?

Chigaev A, Winter SS, Sklar LA. Chigaev A, et al. Among authors: sklar la. Med Hypotheses. 2011 Dec;77(6):1111-3. doi: 10.1016/j.mehy.2011.09.015. Epub 2011 Oct 2. Med Hypotheses. 2011. PMID: 21963354 Free PMC article.

7

Relationship between molecular and cellular dissociation rates for VLA-4/VCAM-1 interaction in the absence of shear stress.

Zwartz G, Chigaev A, Foutz T, Larson RS, Posner R, Sklar LA. Zwartz G, et al. Among authors: sklar la. Biophys J. 2004 Feb;86(2):1243-52. doi: 10.1016/S0006-3495(04)74198-3. Biophys J. 2004. PMID: 14747358 Free PMC article.

8

Galphas-coupled receptor signaling actively down-regulates alpha4beta1-integrin affinity: a possible mechanism for cell de-adhesion.

Chigaev A, Waller A, Amit O, Sklar LA. Chigaev A, et al. Among authors: sklar la. BMC Immunol. 2008 Jun 5;9:26. doi: 10.1186/1471-2172-9-26. BMC Immunol. 2008. PMID: 18534032 Free PMC article.

9

Discovery of very late antigen-4 (VLA-4, alpha4beta1 integrin) allosteric antagonists.

Chigaev A, Wu Y, Williams DB, Smagley Y, Sklar LA. Chigaev A, et al. Among authors: sklar la. J Biol Chem. 2011 Feb 18;286(7):5455-63. doi: 10.1074/jbc.M110.162636. Epub 2010 Dec 3. J Biol Chem. 2011. PMID: 21131351 Free PMC article.

10

Carbon monoxide down-regulates α4β1 integrin-specific ligand binding and cell adhesion: a possible mechanism for cell mobilization.

Chigaev A, Smagley Y, Sklar LA. Chigaev A, et al. Among authors: sklar la. BMC Immunol. 2014 Oct 31;15:52. doi: 10.1186/s12865-014-0052-1. BMC Immunol. 2014. PMID: 25367365 Free PMC article.

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