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Linkage analysis in psychiatric disorders: the emerging picture.
Sklar P. Sklar P. Annu Rev Genomics Hum Genet. 2002;3:371-413. doi: 10.1146/annurev.genom.3.022502.103141. Epub 2002 Apr 15. Annu Rev Genomics Hum Genet. 2002. PMID: 12142356 Review.
Association of a genetic marker at the corticotropin-releasing hormone locus with behavioral inhibition.
Smoller JW, Rosenbaum JF, Biederman J, Kennedy J, Dai D, Racette SR, Laird NM, Kagan J, Snidman N, Hirshfeld-Becker D, Tsuang MT, Sklar PB, Slaugenhaupt SA. Smoller JW, et al. Biol Psychiatry. 2003 Dec 15;54(12):1376-81. doi: 10.1016/s0006-3223(03)00598-5. Biol Psychiatry. 2003. PMID: 14675801
RESULTS: We observed an association between an allele of the CRH-linked locus and BI (p =.015). Among offspring of parents with panic disorder, this association was particularly marked (p =.0009). ...
RESULTS: We observed an association between an allele of the CRH-linked locus and BI (p =.015). Among offspring of parents with panic …
Assessing the impact of population stratification on genetic association studies.
Freedman ML, Reich D, Penney KL, McDonald GJ, Mignault AA, Patterson N, Gabriel SB, Topol EJ, Smoller JW, Pato CN, Pato MT, Petryshen TL, Kolonel LN, Lander ES, Sklar P, Henderson B, Hirschhorn JN, Altshuler D. Freedman ML, et al. Nat Genet. 2004 Apr;36(4):388-93. doi: 10.1038/ng1333. Epub 2004 Mar 28. Nat Genet. 2004. PMID: 15052270
Molecular genetics of attention-deficit/hyperactivity disorder.
Faraone SV, Perlis RH, Doyle AE, Smoller JW, Goralnick JJ, Holmgren MA, Sklar P. Faraone SV, et al. Biol Psychiatry. 2005 Jun 1;57(11):1313-23. doi: 10.1016/j.biopsych.2004.11.024. Epub 2005 Jan 21. Biol Psychiatry. 2005. PMID: 15950004 Review.
The corticotropin-releasing hormone gene and behavioral inhibition in children at risk for panic disorder.
Smoller JW, Yamaki LH, Fagerness JA, Biederman J, Racette S, Laird NM, Kagan J, Snidman N, Faraone SV, Hirshfeld-Becker D, Tsuang MT, Slaugenhaupt SA, Rosenbaum JF, Sklar PB. Smoller JW, et al. Biol Psychiatry. 2005 Jun 15;57(12):1485-92. doi: 10.1016/j.biopsych.2005.02.018. Biol Psychiatry. 2005. PMID: 15953484
The BI phenotype was associated with the microsatellite marker (p=.0016) and three single nucleotide polymorphisms (SNPs), including a SNP in the coding sequence of the gene (p=.023). Haplotype-specific tests revealed association with a haplotype comprising all of t …
The BI phenotype was associated with the microsatellite marker (p=.0016) and three single nucleotide polymorphisms (SNPs), including …
Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q.
McQueen MB, Devlin B, Faraone SV, Nimgaonkar VL, Sklar P, Smoller JW, Abou Jamra R, Albus M, Bacanu SA, Baron M, Barrett TB, Berrettini W, Blacker D, Byerley W, Cichon S, Coryell W, Craddock N, Daly MJ, Depaulo JR, Edenberg HJ, Foroud T, Gill M, Gilliam TC, Hamshere M, Jones I, Jones L, Juo SH, Kelsoe JR, Lambert D, Lange C, Lerer B, Liu J, Maier W, Mackinnon JD, McInnis MG, McMahon FJ, Murphy DL, Nothen MM, Nurnberger JI, Pato CN, Pato MT, Potash JB, Propping P, Pulver AE, Rice JP, Rietschel M, Scheftner W, Schumacher J, Segurado R, Van Steen K, Xie W, Zandi PP, Laird NM. McQueen MB, et al. Am J Hum Genet. 2005 Oct;77(4):582-95. doi: 10.1086/491603. Epub 2005 Aug 15. Am J Hum Genet. 2005. PMID: 16175504 Free PMC article.
Association between the 5HT1B receptor gene (HTR1B) and the inattentive subtype of ADHD.
Smoller JW, Biederman J, Arbeitman L, Doyle AE, Fagerness J, Perlis RH, Sklar P, Faraone SV. Smoller JW, et al. Biol Psychiatry. 2006 Mar 1;59(5):460-7. doi: 10.1016/j.biopsych.2005.07.017. Epub 2005 Sep 28. Biol Psychiatry. 2006. PMID: 16197923
RESULTS: We observed nonsignificant overtransmission of the G861 allele to ADHD offspring (one-tailed p = .07). Single-marker and haplotype tests of a haplotype block encompassing HTR1B revealed no other associations with ADHD. However, this haplotype block was associated …
RESULTS: We observed nonsignificant overtransmission of the G861 allele to ADHD offspring (one-tailed p = .07). Single-marker and hap …
Serotonin gene polymorphisms and bipolar I disorder: focus on the serotonin transporter.
Mansour HA, Talkowski ME, Wood J, Pless L, Bamne M, Chowdari KV, Allen M, Bowden CL, Calabrese J, El-Mallakh RS, Fagiolini A, Faraone SV, Fossey MD, Friedman ES, Gyulai L, Hauser P, Ketter TA, Loftis JM, Marangell LB, Miklowitz DJ, Nierenberg AA, Patel J, Sachs GS, Sklar P, Smoller JW, Thase ME, Frank E, Kupfer DJ, Nimgaonkar VL. Mansour HA, et al. Ann Med. 2005;37(8):590-602. doi: 10.1080/07853890500357428. Ann Med. 2005. PMID: 16338761 Review.
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