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Halting angiogenesis suppresses carcinoma cell invasion.
Skobe M, Rockwell P, Goldstein N, Vosseler S, Fusenig NE. Skobe M, et al. Nat Med. 1997 Nov;3(11):1222-7. doi: 10.1038/nm1197-1222. Nat Med. 1997. PMID: 9359696
Platelet-derived growth factor-BB controls epithelial tumor phenotype by differential growth factor regulation in stromal cells.
Lederle W, Stark HJ, Skobe M, Fusenig NE, Mueller MM. Lederle W, et al. Among authors: skobe m. Am J Pathol. 2006 Nov;169(5):1767-83. doi: 10.2353/ajpath.2006.060120. Am J Pathol. 2006. PMID: 17071599 Free PMC article.
Platelet-derived growth factor-B normalizes micromorphology and vessel function in vascular endothelial growth factor-A-induced squamous cell carcinomas.
Lederle W, Linde N, Heusel J, Bzyl J, Woenne EC, Zwick S, Skobe M, Kiessling F, Fusenig NE, Mueller MM. Lederle W, et al. Among authors: skobe m. Am J Pathol. 2010 Feb;176(2):981-94. doi: 10.2353/ajpath.2010.080998. Epub 2009 Dec 30. Am J Pathol. 2010. PMID: 20042679 Free PMC article.
Activation of the tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth.
Hawighorst T, Skobe M, Streit M, Hong YK, Velasco P, Brown LF, Riccardi L, Lange-Asschenfeldt B, Detmar M. Hawighorst T, et al. Among authors: skobe m. Am J Pathol. 2002 Apr;160(4):1381-92. doi: 10.1016/S0002-9440(10)62565-5. Am J Pathol. 2002. PMID: 11943723 Free PMC article.
Blocking the path of lymphatic vessels.
Skobe M, Dana R. Skobe M, et al. Nat Med. 2009 Sep;15(9):993-4. doi: 10.1038/nm0909-993. Nat Med. 2009. PMID: 19734869 Free PMC article. No abstract available.
Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanoma.
Skobe M, Hamberg LM, Hawighorst T, Schirner M, Wolf GL, Alitalo K, Detmar M. Skobe M, et al. Am J Pathol. 2001 Sep;159(3):893-903. doi: 10.1016/S0002-9440(10)61765-8. Am J Pathol. 2001. PMID: 11549582 Free PMC article.
Tumorigenic conversion of immortal human keratinocytes through stromal cell activation.
Skobe M, Fusenig NE. Skobe M, et al. Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1050-5. doi: 10.1073/pnas.95.3.1050. Proc Natl Acad Sci U S A. 1998. PMID: 9448283 Free PMC article.
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis.
Skobe M, Hawighorst T, Jackson DG, Prevo R, Janes L, Velasco P, Riccardi L, Alitalo K, Claffey K, Detmar M. Skobe M, et al. Nat Med. 2001 Feb;7(2):192-8. doi: 10.1038/84643. Nat Med. 2001. PMID: 11175850
Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas.
Streit M, Velasco P, Brown LF, Skobe M, Richard L, Riccardi L, Lawler J, Detmar M. Streit M, et al. Among authors: skobe m. Am J Pathol. 1999 Aug;155(2):441-52. doi: 10.1016/S0002-9440(10)65140-1. Am J Pathol. 1999. PMID: 10433937 Free PMC article.
Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization.
Bajou K, Noël A, Gerard RD, Masson V, Brunner N, Holst-Hansen C, Skobe M, Fusenig NE, Carmeliet P, Collen D, Foidart JM. Bajou K, et al. Among authors: skobe m. Nat Med. 1998 Aug;4(8):923-8. doi: 10.1038/nm0898-923. Nat Med. 1998. PMID: 9701244
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