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Pancreatic ductal adenocarcinoma and transcription factors: role of c-Myc.
Skoudy A, Hernández-Muñoz I, Navarro P. Skoudy A, et al. J Gastrointest Cancer. 2011 Jun;42(2):76-84. doi: 10.1007/s12029-011-9258-0. J Gastrointest Cancer. 2011. PMID: 21279552 Review.
Role of the basic helix-loop-helix transcription factor p48 in the differentiation phenotype of exocrine pancreas cancer cells.
Adell T, Gómez-Cuadrado A, Skoudy A, Pettengill OS, Longnecker DS, Real FX. Adell T, et al. Cell Growth Differ. 2000 Mar;11(3):137-47. Cell Growth Differ. 2000. PMID: 10768861
Pancreas transcription factor 1 is a heterooligomer of pancreas-specific (p48) and ubiquitous (p75/E2A and p64/HEB) basic helix-loop-helix proteins. ...Serially transplanted acinar DSL6 tumors express p48 whereas DSL6-derived cell lines, and the tumors induced by them, dis …
Pancreas transcription factor 1 is a heterooligomer of pancreas-specific (p48) and ubiquitous (p75/E2A and p64/HEB) basic helix-loop- …
Intermediate filaments as differentiation markers of exocrine pancreas. II. Expression of cytokeratins of complex and stratified epithelia in normal pancreas and in pancreas cancer.
Real FX, Vilá MR, Skoudy A, Ramaekers FC, Corominas JM. Real FX, et al. Int J Cancer. 1993 Jul 9;54(5):720-7. doi: 10.1002/ijc.2910540503. Int J Cancer. 1993. PMID: 7686885
In tumors, CK 14, CK 15/16 and CK 17 were detected in the majority of cases studied; CK 5, CK 10 and CK 13 were present in a sub-population of pancreas cancers. ...
In tumors, CK 14, CK 15/16 and CK 17 were detected in the majority of cases studied; CK 5, CK 10 and CK 13 were present in a sub-popu …
Directed pancreatic acinar differentiation of mouse embryonic stem cells via embryonic signalling molecules and exocrine transcription factors.
Delaspre F, Massumi M, Salido M, Soria B, Ravassard P, Savatier P, Skoudy A. Delaspre F, et al. Among authors: skoudy a. PLoS One. 2013;8(1):e54243. doi: 10.1371/journal.pone.0054243. Epub 2013 Jan 17. PLoS One. 2013. PMID: 23349836 Free PMC article.
Viral-mediated coexpression of Pdx1 and p48 regulates exocrine pancreatic differentiation in mouse ES cells.
Rovira M, Jané-Valbuena J, Marchand M, Savatier P, Real FX, Skoudy A. Rovira M, et al. Among authors: skoudy a. Cloning Stem Cells. 2007 Fall;9(3):327-38. doi: 10.1089/clo.2006.0064. Cloning Stem Cells. 2007. PMID: 17907943
Transforming growth factor (TGF)beta, fibroblast growth factor (FGF) and retinoid signalling pathways promote pancreatic exocrine gene expression in mouse embryonic stem cells.
Skoudy A, Rovira M, Savatier P, Martin F, León-Quinto T, Soria B, Real FX. Skoudy A, et al. Biochem J. 2004 May 1;379(Pt 3):749-56. doi: 10.1042/BJ20031784. Biochem J. 2004. PMID: 14733613 Free PMC article.
Extracellular signalling cues play a major role in the activation of differentiation programmes. Mouse embryonic stem (ES) cells are pluripotent and can differentiate into a wide variety of specialized cells. ...These data indicate that ES cells can undergo exocrine …
Extracellular signalling cues play a major role in the activation of differentiation programmes. Mouse embryonic stem (ES) cells are …
The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma.
Martínez-Romero C, Rooman I, Skoudy A, Guerra C, Molero X, González A, Iglesias M, Lobato T, Bosch A, Barbacid M, Real FX, Hernández-Muñoz I. Martínez-Romero C, et al. Among authors: skoudy a. J Pathol. 2009 Oct;219(2):205-13. doi: 10.1002/path.2585. J Pathol. 2009. PMID: 19585519
Pancreatic ductal adenocarcinoma: cellular origin, signaling pathways and stroma contribution.
Hernández-Muñoz I, Skoudy A, Real FX, Navarro P. Hernández-Muñoz I, et al. Among authors: skoudy a. Pancreatology. 2008;8(4-5):462-9. doi: 10.1159/000151537. Epub 2008 Aug 25. Pancreatology. 2008. PMID: 18724072 Review.
Murine embryonic stem cell-derived pancreatic acinar cells recapitulate features of early pancreatic differentiation.
Rovira M, Delaspre F, Massumi M, Serra SA, Valverde MA, Lloreta J, Dufresne M, Payré B, Konieczny SF, Savatier P, Real FX, Skoudy A. Rovira M, et al. Among authors: skoudy a. Gastroenterology. 2008 Oct;135(4):1301-1310, 1310.e1-5. doi: 10.1053/j.gastro.2008.06.049. Epub 2008 Jun 25. Gastroenterology. 2008. PMID: 18725222 Free PMC article.
Pancreas transcription factor 1alpha expression is regulated in pancreatitis.
Molero X, Adell T, Skoudy A, Padilla MA, Gómez JA, Chalaux E, Malagelada JR, Real FX. Molero X, et al. Among authors: skoudy a. Eur J Clin Invest. 2007 Oct;37(10):791-801. doi: 10.1111/j.1365-2362.2007.01856.x. Eur J Clin Invest. 2007. PMID: 17888090
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