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The MYCN oncogene is a direct target of miR-34a.
Wei JS, Song YK, Durinck S, Chen QR, Cheuk AT, Tsang P, Zhang Q, Thiele CJ, Slack A, Shohet J, Khan J. Wei JS, et al. Among authors: slack a. Oncogene. 2008 Sep 4;27(39):5204-13. doi: 10.1038/onc.2008.154. Epub 2008 May 26. Oncogene. 2008. PMID: 18504438 Free PMC article.
Antisense MBD2 gene therapy inhibits tumorigenesis.
Slack A, Bovenzi V, Bigey P, Ivanov MA, Ramchandani S, Bhattacharya S, tenOever B, Lamrihi B, Scherman D, Szyf M. Slack A, et al. J Gene Med. 2002 Jul-Aug;4(4):381-9. doi: 10.1002/jgm.288. J Gene Med. 2002. PMID: 12124980
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