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Dimerization of MLL fusion proteins immortalizes hematopoietic cells.
Martin ME, Milne TA, Bloyer S, Galoian K, Shen W, Gibbs D, Brock HW, Slany R, Hess JL. Martin ME, et al. Among authors: slany r. Cancer Cell. 2003 Sep;4(3):197-207. doi: 10.1016/s1535-6108(03)00214-9. Cancer Cell. 2003. PMID: 14522254 Free article.
Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization.
Zeisig BB, Milne T, García-Cuéllar MP, Schreiner S, Martin ME, Fuchs U, Borkhardt A, Chanda SK, Walker J, Soden R, Hess JL, Slany RK. Zeisig BB, et al. Among authors: slany rk. Mol Cell Biol. 2004 Jan;24(2):617-28. doi: 10.1128/MCB.24.2.617-628.2004. Mol Cell Biol. 2004. PMID: 14701735 Free PMC article.
77 results