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Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals.
Li N, Alam J, Venkatesan MI, Eiguren-Fernandez A, Schmitz D, Di Stefano E, Slaughter N, Killeen E, Wang X, Huang A, Wang M, Miguel AH, Cho A, Sioutas C, Nel AE. Li N, et al. Among authors: slaughter n. J Immunol. 2004 Sep 1;173(5):3467-81. doi: 10.4049/jimmunol.173.5.3467. J Immunol. 2004. PMID: 15322212 Free article.