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Long-range activation of GREB1 by estrogen receptor via three distal consensus estrogen-responsive elements in breast cancer cells.
Sun J, Nawaz Z, Slingerland JM. Sun J, et al. Among authors: slingerland jm. Mol Endocrinol. 2007 Nov;21(11):2651-62. doi: 10.1210/me.2007-0082. Epub 2007 Jul 31. Mol Endocrinol. 2007. PMID: 17666587
Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer.
Alkarain A, Slingerland J. Alkarain A, et al. Among authors: slingerland j. Breast Cancer Res. 2004;6(1):13-21. doi: 10.1186/bcr722. Epub 2003 Oct 21. Breast Cancer Res. 2004. PMID: 14680481 Free PMC article. Review.
The dual ErbB1/ErbB2 inhibitor, lapatinib (GW572016), cooperates with tamoxifen to inhibit both cell proliferation- and estrogen-dependent gene expression in antiestrogen-resistant breast cancer.
Chu I, Blackwell K, Chen S, Slingerland J. Chu I, et al. Among authors: slingerland j. Cancer Res. 2005 Jan 1;65(1):18-25. Cancer Res. 2005. PMID: 15665275
WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors.
Dhananjayan SC, Ramamoorthy S, Khan OY, Ismail A, Sun J, Slingerland J, O'Malley BW, Nawaz Z. Dhananjayan SC, et al. Among authors: slingerland j. Mol Endocrinol. 2006 Oct;20(10):2343-54. doi: 10.1210/me.2005-0533. Epub 2006 Jun 13. Mol Endocrinol. 2006. PMID: 16772533
p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2.
Chu I, Sun J, Arnaout A, Kahn H, Hanna W, Narod S, Sun P, Tan CK, Hengst L, Slingerland J. Chu I, et al. Among authors: slingerland j. Cell. 2007 Jan 26;128(2):281-94. doi: 10.1016/j.cell.2006.11.049. Cell. 2007. PMID: 17254967 Free PMC article.
Src promotes estrogen-dependent estrogen receptor alpha proteolysis in human breast cancer.
Chu I, Arnaout A, Loiseau S, Sun J, Seth A, McMahon C, Chun K, Hennessy B, Mills GB, Nawaz Z, Slingerland JM. Chu I, et al. Among authors: slingerland jm. J Clin Invest. 2007 Aug;117(8):2205-15. doi: 10.1172/JCI21739. J Clin Invest. 2007. PMID: 17627304 Free PMC article.
mTOR-raptor binds and activates SGK1 to regulate p27 phosphorylation.
Hong F, Larrea MD, Doughty C, Kwiatkowski DJ, Squillace R, Slingerland JM. Hong F, et al. Among authors: slingerland jm. Mol Cell. 2008 Jun 20;30(6):701-11. doi: 10.1016/j.molcel.2008.04.027. Mol Cell. 2008. PMID: 18570873
Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4.
Larrea MD, Liang J, Da Silva T, Hong F, Shao SH, Han K, Dumont D, Slingerland JM. Larrea MD, et al. Among authors: slingerland jm. Mol Cell Biol. 2008 Oct;28(20):6462-72. doi: 10.1128/MCB.02300-07. Epub 2008 Aug 18. Mol Cell Biol. 2008. PMID: 18710949 Free PMC article.
Combined Src and aromatase inhibition impairs human breast cancer growth in vivo and bypass pathways are activated in AZD0530-resistant tumors.
Chen Y, Guggisberg N, Jorda M, Gonzalez-Angulo A, Hennessy B, Mills GB, Tan CK, Slingerland JM. Chen Y, et al. Among authors: slingerland jm. Clin Cancer Res. 2009 May 15;15(10):3396-405. doi: 10.1158/1078-0432.CCR-08-3127. Clin Cancer Res. 2009. PMID: 19451593
Combined Src and ER blockade impairs human breast cancer proliferation in vitro and in vivo.
Chen Y, Alvarez EA, Azzam D, Wander SA, Guggisberg N, Jordà M, Ju Z, Hennessy BT, Slingerland JM. Chen Y, et al. Among authors: slingerland jm. Breast Cancer Res Treat. 2011 Jul;128(1):69-78. doi: 10.1007/s10549-010-1024-7. Epub 2010 Jul 29. Breast Cancer Res Treat. 2011. PMID: 20669046
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