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mTOR signaling in the hippocampus is necessary for memory formation.
Bekinschtein P, Katche C, Slipczuk LN, Igaz LM, Cammarota M, Izquierdo I, Medina JH. Bekinschtein P, et al. Among authors: slipczuk ln. Neurobiol Learn Mem. 2007 Feb;87(2):303-7. doi: 10.1016/j.nlm.2006.08.007. Epub 2006 Sep 26. Neurobiol Learn Mem. 2007. PMID: 17005423
BDNF is essential to promote persistence of long-term memory storage.
Bekinschtein P, Cammarota M, Katche C, Slipczuk L, Rossato JI, Goldin A, Izquierdo I, Medina JH. Bekinschtein P, et al. Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2711-6. doi: 10.1073/pnas.0711863105. Epub 2008 Feb 8. Proc Natl Acad Sci U S A. 2008. PMID: 18263738 Free PMC article.