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Lipid-lowering effects of WAY-121,898, an inhibitor of pancreatic cholesteryl ester hydrolase.
Krause BR, Sliskovic DR, Anderson M, Homan R. Krause BR, et al. Among authors: sliskovic dr. Lipids. 1998 May;33(5):489-98. doi: 10.1007/s11745-998-0232-8. Lipids. 1998. PMID: 9625596
Inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT) as hypocholesterolemic agents: synthesis and structure-activity relationships of novel series of sulfonamides, acylphosphonamides and acylphosphoramidates.
Lee HT, Roark WH, Picard JA, Sliskovic DR, Roth BD, Stanfield RL, Hamelehle KL, Bousley RF, Krause BR. Lee HT, et al. Among authors: sliskovic dr. Bioorg Med Chem Lett. 1998 Feb 3;8(3):289-94. doi: 10.1016/s0960-894x(98)00011-0. Bioorg Med Chem Lett. 1998. PMID: 9871672
alpha-Substituted malonester amides: tools to define the relationship between ACAT inhibition and adrenal toxicity.
Sliskovic DR, Picard JA, O'Brien PM, Liao P, Roark WH, Roth BD, Anderson MA, Mueller SB, Bocan TM, Bousley RF, Hamelehle KL, Homan R, Reindel JF, Stanfield RL, Turluck D, Krause BR. Sliskovic DR, et al. J Med Chem. 1998 Feb 26;41(5):682-90. doi: 10.1021/jm970560h. J Med Chem. 1998. PMID: 9513596
Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. CI-1011: an acyl sulfamate with unique cholesterol-lowering activity in animals fed noncholesterol-supplemented diets.
Lee HT, Sliskovic DR, Picard JA, Roth BD, Wierenga W, Hicks JL, Bousley RF, Hamelehle KL, Homan R, Speyer C, Stanfield RL, Krause BR. Lee HT, et al. Among authors: sliskovic dr. J Med Chem. 1996 Dec 20;39(26):5031-4. doi: 10.1021/jm960674d. J Med Chem. 1996. PMID: 8978833 No abstract available.
Inhibitors of acyl-CoA:cholesterol O-acyltransferase. synthesis and pharmacological activity of (+/-)-2-dodecyl-alpha-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5- acetamide and structurally related tetrazole amide derivatives.
O'Brien PM, Sliskovic DR, Picard JA, Lee HT, Purchase CF 2nd, Roth BD, White AD, Anderson M, Mueller SB, Bocan T, Bousley R, Hamelehle KL, Homan R, Lee P, Krause BR, Reindel JF, Stanfield RL, Turluck D. O'Brien PM, et al. Among authors: sliskovic dr. J Med Chem. 1996 Jun 7;39(12):2354-66. doi: 10.1021/jm960170f. J Med Chem. 1996. PMID: 8691430
Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 17. Structure-activity relationships of several series of compounds derived from N-chlorosulfonyl isocyanate.
Picard JA, O'Brien PM, Sliskovic DR, Anderson MK, Bousley RF, Hamelehle KL, Krause BR, Stanfield RL. Picard JA, et al. Among authors: sliskovic dr. J Med Chem. 1996 Mar 15;39(6):1243-52. doi: 10.1021/jm9509455. J Med Chem. 1996. PMID: 8632431
Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. 6. The first water-soluble ACAT inhibitor with lipid-regulating activity.
Sliskovic DR, Krause BR, Picard JA, Anderson M, Bousley RF, Hamelehle KL, Homan R, Julian TN, Rashidbaigi ZA, Stanfield RL. Sliskovic DR, et al. J Med Chem. 1994 Mar 4;37(5):560-2. doi: 10.1021/jm00031a002. J Med Chem. 1994. PMID: 8126693 No abstract available.
Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 11. Structure-activity relationships of several series of compounds derived from N-(chlorocarbonyl) isocyanate.
Picard JA, Bousley RF, Lee HT, Hamelehle KL, Krause BR, Minton LL, Sliskovic DR, Stanfield RL. Picard JA, et al. Among authors: sliskovic dr. J Med Chem. 1994 Jul 22;37(15):2394-400. doi: 10.1021/jm00041a018. J Med Chem. 1994. PMID: 8057287
Inhibitors of acyl-CoA:cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. 8. Incorporation of amide or amine functionalities into a series of disubstituted ureas and carbamates. Effects on ACAT inhibition in vitro and efficacy in vivo.
O'Brien PM, Sliskovic DR, Blankley CJ, Roth BD, Wilson MW, Hamelehle KL, Krause BR, Stanfield RL. O'Brien PM, et al. Among authors: sliskovic dr. J Med Chem. 1994 Jun 10;37(12):1810-22. doi: 10.1021/jm00038a010. J Med Chem. 1994. PMID: 8021920
Antiatherosclerotic activity of inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase in cholesterol-fed rabbits: a biochemical and morphological evaluation.
Bocan TM, Mazur MJ, Mueller SB, Brown EQ, Sliskovic DR, O'Brien PM, Creswell MW, Lee H, Uhlendorf PD, Roth BD, et al. Bocan TM, et al. Among authors: sliskovic dr. Atherosclerosis. 1994 Nov;111(1):127-42. doi: 10.1016/0021-9150(94)90198-8. Atherosclerosis. 1994. PMID: 7840808
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