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The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans.
Cheng SC, van de Veerdonk FL, Lenardon M, Stoffels M, Plantinga T, Smeekens S, Rizzetto L, Mukaremera L, Preechasuth K, Cavalieri D, Kanneganti TD, van der Meer JW, Kullberg BJ, Joosten LA, Gow NA, Netea MG. Cheng SC, et al. J Leukoc Biol. 2011 Aug;90(2):357-66. doi: 10.1189/jlb.1210702. Epub 2011 Apr 29. J Leukoc Biol. 2011. PMID: 21531876 Free PMC article.
Genetic susceptibility to Candida infections.
Smeekens SP, van de Veerdonk FL, Kullberg BJ, Netea MG. Smeekens SP, et al. EMBO Mol Med. 2013 Jun;5(6):805-13. doi: 10.1002/emmm.201201678. Epub 2013 Apr 30. EMBO Mol Med. 2013. PMID: 23629947 Free PMC article. Review.
Autophagy is redundant for the host defense against systemic Candida albicans infections.
Smeekens SP, Malireddi RK, Plantinga TS, Buffen K, Oosting M, Joosten LA, Kullberg BJ, Perfect JR, Scott WK, van de Veerdonk FL, Xavier RJ, van de Vosse E, Kanneganti TD, Johnson MD, Netea MG. Smeekens SP, et al. Eur J Clin Microbiol Infect Dis. 2014 May;33(5):711-22. doi: 10.1007/s10096-013-2002-x. Epub 2013 Nov 8. Eur J Clin Microbiol Infect Dis. 2014. PMID: 24202731
74 results