Smith DA - Search Results

1

Induction and drug development.

Smith DA. Smith DA. Eur J Pharm Sci. 2000 Sep;11(3):185-9. doi: 10.1016/s0928-0987(00)00107-x. Eur J Pharm Sci. 2000. PMID: 11042223 Review.

2

Analytical approaches to determine cytochrome P450 inhibitory potential of new chemical entities in drug discovery.

Smith D, Sadagopan N, Zientek M, Reddy A, Cohen L. Smith D, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 1;850(1-2):455-63. doi: 10.1016/j.jchromb.2006.12.024. Epub 2006 Dec 30. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17270503

3

Development of an in vitro drug-drug interaction assay to simultaneously monitor five cytochrome P450 isoforms and performance assessment using drug library compounds.

Zientek M, Miller H, Smith D, Dunklee MB, Heinle L, Thurston A, Lee C, Hyland R, Fahmi O, Burdette D. Zientek M, et al. J Pharmacol Toxicol Methods. 2008 Nov-Dec;58(3):206-14. doi: 10.1016/j.vascn.2008.05.131. Epub 2008 Jun 25. J Pharmacol Toxicol Methods. 2008. PMID: 18634893

4

Synthetic strategies to lower affinity for CYP2D6.

Halliday RC, Jones BC, Park BK, Smith DA. Halliday RC, et al. Among authors: smith da. Eur J Drug Metab Pharmacokinet. 1997 Oct-Dec;22(4):291-4. doi: 10.1007/BF03190959. Eur J Drug Metab Pharmacokinet. 1997. PMID: 9512923

5

Putative active site template model for cytochrome P4502C9 (tolbutamide hydroxylase).

Jones BC, Hawksworth G, Horne VA, Newlands A, Morsman J, Tute MS, Smith DA. Jones BC, et al. Among authors: smith da. Drug Metab Dispos. 1996 Feb;24(2):260-6. Drug Metab Dispos. 1996. PMID: 8742240

6

An investigation of the interaction between halofantrine, CYP2D6 and CYP3A4: studies with human liver microsomes and heterologous enzyme expression systems.

Halliday RC, Jones BC, Smith DA, Kitteringham NR, Park BK. Halliday RC, et al. Among authors: smith da. Br J Clin Pharmacol. 1995 Oct;40(4):369-78. doi: 10.1111/j.1365-2125.1995.tb04559.x. Br J Clin Pharmacol. 1995. PMID: 8554939 Free PMC article.

7

Human cytochrome P450s: selectivity and measurement in vivo.

Smith DA, Abel SM, Hyland R, Jones BC. Smith DA, et al. Xenobiotica. 1998 Dec;28(12):1095-128. doi: 10.1080/004982598238859. Xenobiotica. 1998. PMID: 9890156 Review. No abstract available.

8

Pharmacokinetics in Early Drug Research.

Leahy DE, Duncan R, Ahr HJ, Bayliss MK, de Boer AB, Darvas F, Fentem JH, Fry JR, Hopkins R, Houston JB, Karlsson J, Kedderis GL, Pratten MK, Prieto P, Smith DA, Straughan DW. Leahy DE, et al. Among authors: smith da. Altern Lab Anim. 1997 Jan-Feb;25(1):17-31. Altern Lab Anim. 1997. PMID: 26554347 No abstract available.

9

Design of drugs through a consideration of drug metabolism and pharmacokinetics.

Smith DA. Smith DA. Eur J Drug Metab Pharmacokinet. 1994 Jul-Sep;19(3):193-9. doi: 10.1007/BF03188921. Eur J Drug Metab Pharmacokinet. 1994. PMID: 7867661 Review.

10

The disposition of voriconazole in mouse, rat, rabbit, guinea pig, dog, and human.

Roffey SJ, Cole S, Comby P, Gibson D, Jezequel SG, Nedderman AN, Smith DA, Walker DK, Wood N. Roffey SJ, et al. Among authors: smith da. Drug Metab Dispos. 2003 Jun;31(6):731-41. doi: 10.1124/dmd.31.6.731. Drug Metab Dispos. 2003. PMID: 12756205

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