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Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis.
Weston CJ, Shepherd EL, Claridge LC, Rantakari P, Curbishley SM, Tomlinson JW, Hubscher SG, Reynolds GM, Aalto K, Anstee QM, Jalkanen S, Salmi M, Smith DJ, Day CP, Adams DH. Weston CJ, et al. Among authors: smith dj. J Clin Invest. 2015 Feb;125(2):501-20. doi: 10.1172/JCI73722. Epub 2014 Dec 22. J Clin Invest. 2015. PMID: 25562318 Free PMC article. Clinical Trial.
Vascular adhesion protein-1 is elevated in primary sclerosing cholangitis, is predictive of clinical outcome and facilitates recruitment of gut-tropic lymphocytes to liver in a substrate-dependent manner.
Trivedi PJ, Tickle J, Vesterhus MN, Eddowes PJ, Bruns T, Vainio J, Parker R, Smith D, Liaskou E, Thorbjørnsen LW, Hirschfield GM, Auvinen K, Hubscher SG, Salmi M, Adams DH, Weston CJ. Trivedi PJ, et al. Gut. 2018 Jun;67(6):1135-1145. doi: 10.1136/gutjnl-2016-312354. Epub 2017 Apr 20. Gut. 2018. PMID: 28428344 Free PMC article.
Obesity of mice lacking VAP-1/SSAO by Aoc3 gene deletion is reproduced in mice expressing a mutated vascular adhesion protein-1 (VAP-1) devoid of amine oxidase activity.
Jargaud V, Bour S, Tercé F, Collet X, Valet P, Bouloumié A, Guillemot JC, Mauriège P, Jalkanen S, Stolen C, Salmi M, Smith DJ, Carpéné C. Jargaud V, et al. Among authors: smith dj. J Physiol Biochem. 2021 Feb;77(1):141-154. doi: 10.1007/s13105-020-00756-y. Epub 2020 Jul 25. J Physiol Biochem. 2021. PMID: 32712883
A mouse molecular mimic of human vascular adhesion protein-1.
Salmi M, Smith DJ, Bono P, Leu T, Hellman J, Matikainen MT, Jalkanen S. Salmi M, et al. Among authors: smith dj. Mol Immunol. 1997 Nov-Dec;34(16-17):1227-36. doi: 10.1016/s0161-5890(97)00060-6. Mol Immunol. 1997. PMID: 9566769
1,760 results