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1,407 results
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A simplified general method for cluster-sample surveys of health in developing countries.
Bennett S, Woods T, Liyanage WM, Smith DL. Bennett S, et al. Among authors: smith dl. World Health Stat Q. 1991;44(3):98-106. World Health Stat Q. 1991. PMID: 1949887
Minocycline and doxycycline are not beneficial in a model of Huntington's disease.
Smith DL, Woodman B, Mahal A, Sathasivam K, Ghazi-Noori S, Lowden PA, Bates GP, Hockly E. Smith DL, et al. Ann Neurol. 2003 Aug;54(2):186-96. doi: 10.1002/ana.10614. Ann Neurol. 2003. PMID: 12891671
Inhibition of polyglutamine aggregation in R6/2 HD brain slices-complex dose-response profiles.
Smith DL, Portier R, Woodman B, Hockly E, Mahal A, Klunk WE, Li XJ, Wanker E, Murray KD, Bates GP. Smith DL, et al. Neurobiol Dis. 2001 Dec;8(6):1017-26. doi: 10.1006/nbdi.2001.0438. Neurobiol Dis. 2001. PMID: 11741397
SAHA decreases HDAC 2 and 4 levels in vivo and improves molecular phenotypes in the R6/2 mouse model of Huntington's disease.
Mielcarek M, Benn CL, Franklin SA, Smith DL, Woodman B, Marks PA, Bates GP. Mielcarek M, et al. Among authors: smith dl. PLoS One. 2011;6(11):e27746. doi: 10.1371/journal.pone.0027746. Epub 2011 Nov 28. PLoS One. 2011. PMID: 22140466 Free PMC article.
HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration.
Mielcarek M, Landles C, Weiss A, Bradaia A, Seredenina T, Inuabasi L, Osborne GF, Wadel K, Touller C, Butler R, Robertson J, Franklin SA, Smith DL, Park L, Marks PA, Wanker EE, Olson EN, Luthi-Carter R, van der Putten H, Beaumont V, Bates GP. Mielcarek M, et al. Among authors: smith dl. PLoS Biol. 2013 Nov;11(11):e1001717. doi: 10.1371/journal.pbio.1001717. Epub 2013 Nov 26. PLoS Biol. 2013. PMID: 24302884 Free PMC article.
SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington's Disease Mice.
Tulino R, Benjamin AC, Jolinon N, Smith DL, Chini EN, Carnemolla A, Bates GP. Tulino R, et al. Among authors: smith dl. PLoS One. 2016 Jan 27;11(1):e0145425. doi: 10.1371/journal.pone.0145425. eCollection 2016. PLoS One. 2016. PMID: 26815359 Free PMC article.
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease.
Hockly E, Richon VM, Woodman B, Smith DL, Zhou X, Rosa E, Sathasivam K, Ghazi-Noori S, Mahal A, Lowden PA, Steffan JS, Marsh JL, Thompson LM, Lewis CM, Marks PA, Bates GP. Hockly E, et al. Among authors: smith dl. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):2041-6. doi: 10.1073/pnas.0437870100. Epub 2003 Feb 7. Proc Natl Acad Sci U S A. 2003. PMID: 12576549 Free PMC article.
Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.
Mielcarek M, Inuabasi L, Bondulich MK, Muller T, Osborne GF, Franklin SA, Smith DL, Neueder A, Rosinski J, Rattray I, Protti A, Bates GP. Mielcarek M, et al. Among authors: smith dl. PLoS Genet. 2014 Aug 7;10(8):e1004550. doi: 10.1371/journal.pgen.1004550. eCollection 2014 Aug. PLoS Genet. 2014. PMID: 25101683 Free PMC article.
Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease.
Sathasivam K, Neueder A, Gipson TA, Landles C, Benjamin AC, Bondulich MK, Smith DL, Faull RL, Roos RA, Howland D, Detloff PJ, Housman DE, Bates GP. Sathasivam K, et al. Among authors: smith dl. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2366-70. doi: 10.1073/pnas.1221891110. Epub 2013 Jan 22. Proc Natl Acad Sci U S A. 2013. PMID: 23341618 Free PMC article.
Frequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell-type-specific.
Jansen AH, van Hal M, Op den Kelder IC, Meier RT, de Ruiter AA, Schut MH, Smith DL, Grit C, Brouwer N, Kamphuis W, Boddeke HW, den Dunnen WF, van Roon WM, Bates GP, Hol EM, Reits EA. Jansen AH, et al. Among authors: smith dl. Glia. 2017 Jan;65(1):50-61. doi: 10.1002/glia.23050. Epub 2016 Sep 12. Glia. 2017. PMID: 27615381 Free PMC article.
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