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AKAP-Lbc nucleates a protein kinase D activation scaffold.
Carnegie GK, Smith FD, McConnachie G, Langeberg LK, Scott JD. Carnegie GK, et al. Among authors: smith fd. Mol Cell. 2004 Sep 24;15(6):889-99. doi: 10.1016/j.molcel.2004.09.015. Mol Cell. 2004. PMID: 15383279
The where's and when's of kinase anchoring.
Smith FD, Langeberg LK, Scott JD. Smith FD, et al. Trends Biochem Sci. 2006 Jun;31(6):316-23. doi: 10.1016/j.tibs.2006.04.009. Epub 2006 May 11. Trends Biochem Sci. 2006. PMID: 16690317 Review.
AKAP18 contains a phosphoesterase domain that binds AMP.
Gold MG, Smith FD, Scott JD, Barford D. Gold MG, et al. Among authors: smith fd. J Mol Biol. 2008 Feb 1;375(5):1329-43. doi: 10.1016/j.jmb.2007.11.037. Epub 2007 Nov 22. J Mol Biol. 2008. PMID: 18082768 Free PMC article.
AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway.
Carnegie GK, Soughayer J, Smith FD, Pedroja BS, Zhang F, Diviani D, Bristow MR, Kunkel MT, Newton AC, Langeberg LK, Scott JD. Carnegie GK, et al. Among authors: smith fd. Mol Cell. 2008 Oct 24;32(2):169-79. doi: 10.1016/j.molcel.2008.08.030. Mol Cell. 2008. PMID: 18951085 Free PMC article.
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade.
Smith FD, Langeberg LK, Cellurale C, Pawson T, Morrison DK, Davis RJ, Scott JD. Smith FD, et al. Nat Cell Biol. 2010 Dec;12(12):1242-9. doi: 10.1038/ncb2130. Epub 2010 Nov 21. Nat Cell Biol. 2010. PMID: 21102438 Free PMC article.
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