Smith JL - Search Results

1

Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction.

Biering SB, Akey DL, Wong MP, Brown WC, Lo NTN, Puerta-Guardo H, Tramontini Gomes de Sousa F, Wang C, Konwerski JR, Espinosa DA, Bockhaus NJ, Glasner DR, Li J, Blanc SF, Juan EY, Elledge SJ, Mina MJ, Beatty PR, Smith JL, Harris E. Biering SB, et al. Among authors: smith jl. Science. 2021 Jan 8;371(6525):194-200. doi: 10.1126/science.abc0476. Science. 2021. PMID: 33414220 Free PMC article.

2

Structural basis for macrolactonization by the pikromycin thioesterase.

Akey DL, Kittendorf JD, Giraldes JW, Fecik RA, Sherman DH, Smith JL. Akey DL, et al. Among authors: smith jl. Nat Chem Biol. 2006 Oct;2(10):537-42. doi: 10.1038/nchembio824. Epub 2006 Sep 10. Nat Chem Biol. 2006. PMID: 16969372

3

Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels.

Giraldes JW, Akey DL, Kittendorf JD, Sherman DH, Smith JL, Fecik RA. Giraldes JW, et al. Among authors: smith jl. Nat Chem Biol. 2006 Oct;2(10):531-6. doi: 10.1038/nchembio822. Epub 2006 Sep 10. Nat Chem Biol. 2006. PMID: 16969373

4

GNAT-like strategy for polyketide chain initiation.

Gu L, Geders TW, Wang B, Gerwick WH, Håkansson K, Smith JL, Sherman DH. Gu L, et al. Among authors: smith jl. Science. 2007 Nov 9;318(5852):970-4. doi: 10.1126/science.1148790. Science. 2007. PMID: 17991863

5

An enzyme assembly line.

Smith JL, Sherman DH. Smith JL, et al. Science. 2008 Sep 5;321(5894):1304-5. doi: 10.1126/science.1163785. Science. 2008. PMID: 18772425 Free PMC article. No abstract available.

6

Mocr: a novel fusion tag for enhancing solubility that is compatible with structural biology applications.

DelProposto J, Majmudar CY, Smith JL, Brown WC. DelProposto J, et al. Among authors: smith jl. Protein Expr Purif. 2009 Jan;63(1):40-9. doi: 10.1016/j.pep.2008.08.011. Epub 2008 Sep 12. Protein Expr Purif. 2009. PMID: 18824232 Free PMC article.

7

Structure and functional analysis of RifR, the type II thioesterase from the rifamycin biosynthetic pathway.

Claxton HB, Akey DL, Silver MK, Admiraal SJ, Smith JL. Claxton HB, et al. Among authors: smith jl. J Biol Chem. 2009 Feb 20;284(8):5021-9. doi: 10.1074/jbc.M808604200. Epub 2008 Dec 22. J Biol Chem. 2009. PMID: 19103602 Free PMC article.

8

Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway.

Akey DL, Razelun JR, Tehranisa J, Sherman DH, Gerwick WH, Smith JL. Akey DL, et al. Among authors: smith jl. Structure. 2010 Jan 13;18(1):94-105. doi: 10.1016/j.str.2009.10.018. Structure. 2010. PMID: 20152156 Free PMC article.

9

Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.

Scaglione JB, Akey DL, Sullivan R, Kittendorf JD, Rath CM, Kim ES, Smith JL, Sherman DH. Scaglione JB, et al. Among authors: smith jl. Angew Chem Int Ed Engl. 2010 Aug 2;49(33):5726-30. doi: 10.1002/anie.201000032. Angew Chem Int Ed Engl. 2010. PMID: 20623733 Free PMC article. No abstract available.

10

A general scheme for synthesis of substrate-based polyketide labels for acyl carrier proteins.

Leggans EK, Akey DL, Smith JL, Fecik RA. Leggans EK, et al. Among authors: smith jl. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5939-42. doi: 10.1016/j.bmcl.2010.05.089. Epub 2010 May 25. Bioorg Med Chem Lett. 2010. PMID: 20801036 Free PMC article.

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