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Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.
Husson H, Moreno S, Smith LA, Smith MM, Russo RJ, Pitstick R, Sergeev M, Ledbetter SR, Bukanov NO, Lane M, Zhang K, Billot K, Carlson G, Shah J, Meijer L, Beier DR, Ibraghimov-Beskrovnaya O. Husson H, et al. Among authors: smith mm, smith la. Hum Mol Genet. 2016 Jun 1;25(11):2245-2255. doi: 10.1093/hmg/ddw093. Epub 2016 Apr 5. Hum Mol Genet. 2016. PMID: 27053712 Free PMC article.
Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models.
Natoli TA, Smith LA, Rogers KA, Wang B, Komarnitsky S, Budman Y, Belenky A, Bukanov NO, Dackowski WR, Husson H, Russo RJ, Shayman JA, Ledbetter SR, Leonard JP, Ibraghimov-Beskrovnaya O. Natoli TA, et al. Among authors: smith la. Nat Med. 2010 Jul;16(7):788-92. doi: 10.1038/nm.2171. Epub 2010 Jun 20. Nat Med. 2010. PMID: 20562878 Free PMC article.
697 results