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Replication origins: determinants or consequences of nuclear organization?
Marks AB, Smith OK, Aladjem MI. Marks AB, et al. Among authors: smith ok. Curr Opin Genet Dev. 2016 Apr;37:67-75. doi: 10.1016/j.gde.2015.11.008. Epub 2016 Feb 2. Curr Opin Genet Dev. 2016. PMID: 26845042 Free PMC article. Review.
The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin.
Jang SM, Zhang Y, Utani K, Fu H, Redon CE, Marks AB, Smith OK, Redmond CJ, Baris AM, Tulchinsky DA, Aladjem MI. Jang SM, et al. Among authors: smith ok. Nat Commun. 2018 Jul 17;9(1):2782. doi: 10.1038/s41467-018-05177-6. Nat Commun. 2018. PMID: 30018425 Free PMC article.
Phosphorylated SIRT1 associates with replication origins to prevent excess replication initiation and preserve genomic stability.
Utani K, Fu H, Jang SM, Marks AB, Smith OK, Zhang Y, Redon CE, Shimizu N, Aladjem MI. Utani K, et al. Among authors: smith ok. Nucleic Acids Res. 2017 Jul 27;45(13):7807-7824. doi: 10.1093/nar/gkx468. Nucleic Acids Res. 2017. PMID: 28549174 Free PMC article.
Temporal association of ORCA/LRWD1 to late-firing origins during G1 dictates heterochromatin replication and organization.
Wang Y, Khan A, Marks AB, Smith OK, Giri S, Lin YC, Creager R, MacAlpine DM, Prasanth KV, Aladjem MI, Prasanth SG. Wang Y, et al. Among authors: smith ok. Nucleic Acids Res. 2017 Mar 17;45(5):2490-2502. doi: 10.1093/nar/gkw1211. Nucleic Acids Res. 2017. PMID: 27924004 Free PMC article.
A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells.
Zhang Y, Huang L, Fu H, Smith OK, Lin CM, Utani K, Rao M, Reinhold WC, Redon CE, Ryan M, Kim R, You Y, Hanna H, Boisclair Y, Long Q, Aladjem MI. Zhang Y, et al. Among authors: smith ok. Nat Commun. 2016 Jun 8;7:11748. doi: 10.1038/ncomms11748. Nat Commun. 2016. PMID: 27272143 Free PMC article.
Distinct epigenetic features of differentiation-regulated replication origins.
Smith OK, Kim R, Fu H, Martin MM, Lin CM, Utani K, Zhang Y, Marks AB, Lalande M, Chamberlain S, Libbrecht MW, Bouhassira EE, Ryan MC, Noble WS, Aladjem MI. Smith OK, et al. Epigenetics Chromatin. 2016 May 10;9:18. doi: 10.1186/s13072-016-0067-3. eCollection 2016. Epigenetics Chromatin. 2016. PMID: 27168766 Free PMC article.
ColoWeb: a resource for analysis of colocalization of genomic features.
Kim R, Smith OK, Wong WC, Ryan AM, Ryan MC, Aladjem MI. Kim R, et al. Among authors: smith ok. BMC Genomics. 2015 Feb 28;16(1):142. doi: 10.1186/s12864-015-1345-3. BMC Genomics. 2015. PMID: 25887597 Free PMC article.
Chromatin-Associated RNA Sequencing (ChAR-seq).
Jukam D, Limouse C, Smith OK, Risca VI, Bell JC, Straight AF. Jukam D, et al. Among authors: smith ok. Curr Protoc Mol Biol. 2019 Apr;126(1):e87. doi: 10.1002/cpmb.87. Epub 2019 Feb 20. Curr Protoc Mol Biol. 2019. PMID: 30786161
Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency.
Gineau L, Cognet C, Kara N, Lach FP, Dunne J, Veturi U, Picard C, Trouillet C, Eidenschenk C, Aoufouchi S, Alcaïs A, Smith O, Geissmann F, Feighery C, Abel L, Smogorzewska A, Stillman B, Vivier E, Casanova JL, Jouanguy E. Gineau L, et al. Among authors: smith o. J Clin Invest. 2012 Mar;122(3):821-32. doi: 10.1172/JCI61014. Epub 2012 Feb 22. J Clin Invest. 2012. PMID: 22354167 Free PMC article.
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