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11,613 results
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Insulinotropic actions of exendin-4 and glucagon-like peptide-1 in vivo and in vitro.
Parkes DG, Pittner R, Jodka C, Smith P, Young A. Parkes DG, et al. Among authors: smith p. Metabolism. 2001 May;50(5):583-9. doi: 10.1053/meta.2001.22519. Metabolism. 2001. PMID: 11319721
A novel long-acting glucose-dependent insulinotropic peptide analogue: enhanced efficacy in normal and diabetic rodents.
Tatarkiewicz K, Hargrove DM, Jodka CM, Gedulin BR, Smith PA, Hoyt JA, Lwin A, Collins L, Mamedova L, Levy OE, D'Souza L, Janssen S, Srivastava V, Ghosh SS, Parkes DG. Tatarkiewicz K, et al. Among authors: smith pa. Diabetes Obes Metab. 2014 Jan;16(1):75-85. doi: 10.1111/dom.12181. Epub 2013 Aug 19. Diabetes Obes Metab. 2014. PMID: 23859463 Free PMC article.
Glucoregulatory effects and prolonged duration of action of davalintide: a novel amylinomimetic peptide.
Mack CM, Smith PA, Athanacio JR, Xu K, Wilson JK, Reynolds JM, Jodka CM, Lu MG, Parkes DG. Mack CM, et al. Among authors: smith pa. Diabetes Obes Metab. 2011 Dec;13(12):1105-13. doi: 10.1111/j.1463-1326.2011.01465.x. Diabetes Obes Metab. 2011. PMID: 21733060
Effects of PYY[3-36] in rodent models of diabetes and obesity.
Pittner RA, Moore CX, Bhavsar SP, Gedulin BR, Smith PA, Jodka CM, Parkes DG, Paterniti JR, Srivastava VP, Young AA. Pittner RA, et al. Among authors: smith pa. Int J Obes Relat Metab Disord. 2004 Aug;28(8):963-71. doi: 10.1038/sj.ijo.0802696. Int J Obes Relat Metab Disord. 2004. PMID: 15197409
Davalintide (AC2307), a novel amylin-mimetic peptide: enhanced pharmacological properties over native amylin to reduce food intake and body weight.
Mack CM, Soares CJ, Wilson JK, Athanacio JR, Turek VF, Trevaskis JL, Roth JD, Smith PA, Gedulin B, Jodka CM, Roland BL, Adams SH, Lwin A, Herich J, Laugero KD, Vu C, Pittner R, Paterniti JR Jr, Hanley M, Ghosh S, Parkes DG. Mack CM, et al. Among authors: smith pa. Int J Obes (Lond). 2010 Feb;34(2):385-95. doi: 10.1038/ijo.2009.238. Epub 2009 Nov 24. Int J Obes (Lond). 2010. PMID: 19935749
Exenatide does not evoke pancreatitis and attenuates chemically induced pancreatitis in normal and diabetic rodents.
Tatarkiewicz K, Smith PA, Sablan EJ, Polizzi CJ, Aumann DE, Villescaz C, Hargrove DM, Gedulin BR, Lu MG, Adams L, Whisenant T, Roy D, Parkes DG. Tatarkiewicz K, et al. Am J Physiol Endocrinol Metab. 2010 Dec;299(6):E1076-86. doi: 10.1152/ajpendo.00479.2010. Epub 2010 Oct 5. Am J Physiol Endocrinol Metab. 2010. PMID: 20923958 Free PMC article.
Pharmacokinetics and pharmacodynamics of exenatide following alternate routes of administration.
Gedulin BR, Smith PA, Jodka CM, Chen K, Bhavsar S, Nielsen LL, Parkes DG, Young AA. Gedulin BR, et al. Int J Pharm. 2008 May 22;356(1-2):231-8. doi: 10.1016/j.ijpharm.2008.01.015. Epub 2008 Jan 17. Int J Pharm. 2008. PMID: 18291606
Exenatide (exendin-4) improves insulin sensitivity and {beta}-cell mass in insulin-resistant obese fa/fa Zucker rats independent of glycemia and body weight.
Gedulin BR, Nikoulina SE, Smith PA, Gedulin G, Nielsen LL, Baron AD, Parkes DG, Young AA. Gedulin BR, et al. Endocrinology. 2005 Apr;146(4):2069-76. doi: 10.1210/en.2004-1349. Epub 2004 Dec 23. Endocrinology. 2005. PMID: 15618356
Biological activity of AC3174, a peptide analog of exendin-4.
Hargrove DM, Kendall ES, Reynolds JM, Lwin AN, Herich JP, Smith PA, Gedulin BR, Flanagan SD, Jodka CM, Hoyt JA, McCowen KM, Parkes DG, Anderson CM. Hargrove DM, et al. Among authors: smith pa. Regul Pept. 2007 Jun 7;141(1-3):113-9. doi: 10.1016/j.regpep.2006.12.021. Epub 2007 Jan 11. Regul Pept. 2007. PMID: 17292977
Nonpeptide endothelin receptor antagonists. VI: Pharmacological characterization of SB 217242, a potent and highly bioavailable endothelin receptor antagonist.
Ohlstein EH, Nambi P, Lago A, Hay DW, Beck G, Fong KL, Eddy EP, Smith P, Ellens H, Elliott JD. Ohlstein EH, et al. Among authors: smith p. J Pharmacol Exp Ther. 1996 Feb;276(2):609-15. J Pharmacol Exp Ther. 1996. PMID: 8632328
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