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1,395 results
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Insulin sensitisation in the treatment of Type 2 diabetes.
Tadayyon M, Smith SA. Tadayyon M, et al. Among authors: smith sa. Expert Opin Investig Drugs. 2003 Mar;12(3):307-24. doi: 10.1517/13543784.12.3.307. Expert Opin Investig Drugs. 2003. PMID: 12605557 Review.
Non-thiazolidinedione antihyperglycaemic agents. Part 3: The effects of stereochemistry on the potency of alpha-methoxy-beta-phenylpropanoic acids.
Haigh D, Allen G, Birrell HC, Buckle DR, Cantello BC, Eggleston DS, Haltiwanger RC, Holder JC, Lister CA, Pinto IL, Rami HK, Sime JT, Smith SA, Sweeney JD. Haigh D, et al. Among authors: smith sa. Bioorg Med Chem. 1999 May;7(5):821-30. doi: 10.1016/s0968-0896(99)00034-6. Bioorg Med Chem. 1999. PMID: 10400335
Rosiglitazone prevents the onset of hyperglycaemia and proteinuria in the Zucker diabetic fatty rat.
Smith SA, Lister CA, Toseland CD, Buckingham RE. Smith SA, et al. Diabetes Obes Metab. 2000 Dec;2(6):363-72. doi: 10.1046/j.1463-1326.2000.00099.x. Diabetes Obes Metab. 2000. PMID: 11225966
Peroxisomal proliferate-activated receptors and the regulation of lipid oxidation and adipogenesis.
Smith SA. Smith SA. Biochem Soc Trans. 1997 Nov;25(4):1242-8. doi: 10.1042/bst0251242. Biochem Soc Trans. 1997. PMID: 9449984 Review. No abstract available.
Antidiabetic efficacy of BRL 49653, a potent orally active insulin sensitizing agent, assessed in the C57BL/KsJ db/db diabetic mouse by non-invasive 1H NMR studies of urine.
Connor SC, Hughes MG, Moore G, Lister CA, Smith SA. Connor SC, et al. Among authors: smith sa. J Pharm Pharmacol. 1997 Mar;49(3):336-44. doi: 10.1111/j.2042-7158.1997.tb06808.x. J Pharm Pharmacol. 1997. PMID: 9231358
Central role of the adipocyte in the insulin-sensitising and cardiovascular risk modifying actions of the thiazolidinediones.
Smith SA. Smith SA. Biochimie. 2003 Dec;85(12):1219-30. doi: 10.1016/j.biochi.2003.10.010. Biochimie. 2003. PMID: 14739074 Review.
PPARalpha activation by Wy 14643 induces transactivation of the rat UCP-1 promoter without increasing UCP-1 mRNA levels and attenuates PPARgamma-mediated increases in UCP-1 mRNA levels induced by rosiglitazone in fetal rat brown adipocytes.
Teruel T, Clapham JC, Smith SA. Teruel T, et al. Among authors: smith sa. Biochem Biophys Res Commun. 1999 Oct 22;264(2):311-5. doi: 10.1006/bbrc.1999.1526. Biochem Biophys Res Commun. 1999. PMID: 10529360
Synergistic activation of UCP-3 expression in cultured fetal rat brown adipocytes by PPARalpha and PPARgamma ligands.
Teruel T, Smith SA, Peterson J, Clapham JC. Teruel T, et al. Among authors: smith sa. Biochem Biophys Res Commun. 2000 Jul 5;273(2):560-4. doi: 10.1006/bbrc.2000.2982. Biochem Biophys Res Commun. 2000. PMID: 10873645
The identification of a potent, water soluble inhibitor of lipoprotein-associated phospholipase A2.
Boyd HF, Hammond B, Hickey DM, Ife RJ, Leach CA, Lewis VA, Macphee CH, Milliner KJ, Pinto IL, Smith SA, Stansfield IG, Theobald CJ, Whittaker CM. Boyd HF, et al. Among authors: smith sa. Bioorg Med Chem Lett. 2001 Mar 12;11(5):701-4. doi: 10.1016/s0960-894x(01)00038-5. Bioorg Med Chem Lett. 2001. PMID: 11266173
1-(Arylpiperazinylamidoalkyl)-pyrimidones: orally active inhibitors of lipoprotein-associated phospholipase A(2).
Bloomer JC, Boyd HF, Hickey DM, Ife RJ, Leach CA, Macphee CH, Milliner KJ, Pinto IL, Rawlings DA, Smith SA, Stansfield IG, Stanway SJ, Taylor MA, Theobald CJ, Whittaker CM. Bloomer JC, et al. Among authors: smith sa. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1925-9. doi: 10.1016/s0960-894x(01)00346-8. Bioorg Med Chem Lett. 2001. PMID: 11459662
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