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Harnessing the protective potential of HIV-1 neutralizing antibodies.
Smith SA, Derdeyn CA. Smith SA, et al. F1000Res. 2016 Jan 5;5:F1000 Faculty Rev-20. doi: 10.12688/f1000research.7254.1. eCollection 2016. F1000Res. 2016. PMID: 26918160 Free PMC article. Review.
Characterization and Implementation of a Diverse Simian Immunodeficiency Virus SIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope.
Kilgore KM, Murphy MK, Burton SL, Wetzel KS, Smith SA, Xiao P, Reddy S, Francella N, Sodora DL, Silvestri G, Cole KS, Villinger F, Robinson JE, Pulendran B, Hunter E, Collman RG, Amara RR, Derdeyn CA. Kilgore KM, et al. J Virol. 2015 Aug;89(16):8130-51. doi: 10.1128/JVI.01221-14. Epub 2015 May 27. J Virol. 2015. PMID: 26018167 Free PMC article.
Signatures in Simian Immunodeficiency Virus SIVsmE660 Envelope gp120 Are Associated with Mucosal Transmission but Not Vaccination Breakthrough in Rhesus Macaques.
Smith SA, Kilgore KM, Kasturi SP, Pulendran B, Hunter E, Amara RR, Derdeyn CA. Smith SA, et al. J Virol. 2015 Dec 16;90(4):1880-7. doi: 10.1128/JVI.02711-15. Print 2016 Feb 15. J Virol. 2015. PMID: 26676777 Free PMC article.
Diversification in the HIV-1 Envelope Hyper-variable Domains V2, V4, and V5 and Higher Probability of Transmitted/Founder Envelope Glycosylation Favor the Development of Heterologous Neutralization Breadth.
Smith SA, Burton SL, Kilembe W, Lakhi S, Karita E, Price M, Allen S, Hunter E, Derdeyn CA. Smith SA, et al. PLoS Pathog. 2016 Nov 16;12(11):e1005989. doi: 10.1371/journal.ppat.1005989. eCollection 2016 Nov. PLoS Pathog. 2016. PMID: 27851829 Free PMC article.
Breakthrough of SIV strain smE660 challenge in SIV strain mac239-vaccinated rhesus macaques despite potent autologous neutralizing antibody responses.
Burton SL, Kilgore KM, Smith SA, Reddy S, Hunter E, Robinson HL, Silvestri G, Amara RR, Derdeyn CA. Burton SL, et al. Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10780-5. doi: 10.1073/pnas.1509731112. Epub 2015 Aug 10. Proc Natl Acad Sci U S A. 2015. PMID: 26261312 Free PMC article.
A pathway to HIV-1 neutralization breadth.
Smith SA, Derdeyn CA. Smith SA, et al. Nat Med. 2015 Nov;21(11):1246-7. doi: 10.1038/nm.3989. Nat Med. 2015. PMID: 26540383 Free PMC article.
VH1-69 Utilizing Antibodies Are Capable of Mediating Non-neutralizing Fc-Mediated Effector Functions Against the Transmitted/Founder gp120.
Smith SA, Burton SL, Kilembe W, Lakhi S, Karita E, Price M, Allen S, Derdeyn CA. Smith SA, et al. Front Immunol. 2019 Jan 15;9:3163. doi: 10.3389/fimmu.2018.03163. eCollection 2018. Front Immunol. 2019. PMID: 30697215 Free PMC article.
CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy.
Cartwright EK, Spicer L, Smith SA, Lee D, Fast R, Paganini S, Lawson BO, Nega M, Easley K, Schmitz JE, Bosinger SE, Paiardini M, Chahroudi A, Vanderford TH, Estes JD, Lifson JD, Derdeyn CA, Silvestri G. Cartwright EK, et al. Immunity. 2016 Sep 20;45(3):656-668. doi: 10.1016/j.immuni.2016.08.018. Immunity. 2016. PMID: 27653601 Free PMC article.
Use of Human Hybridoma Technology To Isolate Human Monoclonal Antibodies.
Smith SA, Crowe JE Jr. Smith SA, et al. Microbiol Spectr. 2015 Feb;3(1):AID-0027-2014. doi: 10.1128/microbiolspec.AID-0027-2014. Microbiol Spectr. 2015. PMID: 26104564 Review.
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