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Increased fat intake, impaired fat oxidation, and failure of fat cell proliferation result in ectopic fat storage, insulin resistance, and type 2 diabetes mellitus.
Ravussin E, Smith SR. Ravussin E, et al. Among authors: smith sr. Ann N Y Acad Sci. 2002 Jun;967:363-78. doi: 10.1111/j.1749-6632.2002.tb04292.x. Ann N Y Acad Sci. 2002. PMID: 12079864 Review.
Effects of diets enriched in saturated (palmitic), monounsaturated (oleic), or trans (elaidic) fatty acids on insulin sensitivity and substrate oxidation in healthy adults.
Lovejoy JC, Smith SR, Champagne CM, Most MM, Lefevre M, DeLany JP, Denkins YM, Rood JC, Veldhuis J, Bray GA. Lovejoy JC, et al. Among authors: smith sr. Diabetes Care. 2002 Aug;25(8):1283-8. doi: 10.2337/diacare.25.8.1283. Diabetes Care. 2002. PMID: 12145222 Clinical Trial.
The influence of different fats and fatty acids on obesity, insulin resistance and inflammation.
Bray GA, Lovejoy JC, Smith SR, DeLany JP, Lefevre M, Hwang D, Ryan DH, York DA. Bray GA, et al. Among authors: smith sr. J Nutr. 2002 Sep;132(9):2488-91. doi: 10.1093/jn/132.9.2488. J Nutr. 2002. PMID: 12221198 Review.
A 9-mo randomized clinical trial comparing fat-substituted and fat-reduced diets in healthy obese men: the Ole Study.
Bray GA, Lovejoy JC, Most-Windhauser M, Smith SR, Volaufova J, Denkins Y, de Jonge L, Rood J, Lefevre M, Eldridge AL, Peters JC. Bray GA, et al. Among authors: smith sr. Am J Clin Nutr. 2002 Nov;76(5):928-34. doi: 10.1093/ajcn/76.5.928. Am J Clin Nutr. 2002. PMID: 12399262 Clinical Trial.
Human mesenchymal stem cells as an in vitro model for human adipogenesis.
Janderová L, McNeil M, Murrell AN, Mynatt RL, Smith SR. Janderová L, et al. Among authors: smith sr. Obes Res. 2003 Jan;11(1):65-74. doi: 10.1038/oby.2003.11. Obes Res. 2003. PMID: 12529487
Emerging paradigms for understanding fatness and diabetes risk.
Smith SR, Ravussin E. Smith SR, et al. Curr Diab Rep. 2002 Jun;2(3):223-30. doi: 10.1007/s11892-002-0087-1. Curr Diab Rep. 2002. PMID: 12643177 Review.
A promoter genotype and oxidative stress potentially link resistin to human insulin resistance.
Smith SR, Bai F, Charbonneau C, Janderová L, Argyropoulos G. Smith SR, et al. Diabetes. 2003 Jul;52(7):1611-8. doi: 10.2337/diabetes.52.7.1611. Diabetes. 2003. PMID: 12829623
Agouti expression in human adipose tissue: functional consequences and increased expression in type 2 diabetes.
Smith SR, Gawronska-Kozak B, Janderová L, Nguyen T, Murrell A, Stephens JM, Mynatt RL. Smith SR, et al. Diabetes. 2003 Dec;52(12):2914-22. doi: 10.2337/diabetes.52.12.2914. Diabetes. 2003. PMID: 14633851
The effect of pioglitazone on peroxisome proliferator-activated receptor-gamma target genes related to lipid storage in vivo.
Bogacka I, Xie H, Bray GA, Smith SR. Bogacka I, et al. Among authors: smith sr. Diabetes Care. 2004 Jul;27(7):1660-7. doi: 10.2337/diacare.27.7.1660. Diabetes Care. 2004. PMID: 15220243 Clinical Trial.
Effect of a dietary herbal supplement containing caffeine and ephedra on weight, metabolic rate, and body composition.
Greenway FL, De Jonge L, Blanchard D, Frisard M, Smith SR. Greenway FL, et al. Among authors: smith sr. Obes Res. 2004 Jul;12(7):1152-7. doi: 10.1038/oby.2004.144. Obes Res. 2004. PMID: 15292480 Clinical Trial.
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