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C-terminal Ser/Pro-Thr-Glu-Leu tetrapeptides of prostaglandin endoperoxide H synthases-1 and -2 target the enzymes to the endoplasmic reticulum.
Song I, Smith WL. Song I, et al. Among authors: smith wl. Arch Biochem Biophys. 1996 Oct 1;334(1):67-72. doi: 10.1006/abbi.1996.0430. Arch Biochem Biophys. 1996. PMID: 8837740
Molecular biology of prostanoid biosynthetic enzymes and receptors.
Smith W. Smith W. Adv Exp Med Biol. 1997;400B:989-1011. Adv Exp Med Biol. 1997. PMID: 9547656 Review. No abstract available.
The enzymology of prostaglandin endoperoxide H synthases-1 and -2.
Smith WL, Song I. Smith WL, et al. Prostaglandins Other Lipid Mediat. 2002 Aug;68-69:115-28. doi: 10.1016/s0090-6980(02)00025-4. Prostaglandins Other Lipid Mediat. 2002. PMID: 12432913 Review.
Different suicide inactivation processes for the peroxidase and cyclooxygenase activities of prostaglandin endoperoxide H synthase-1.
Song I, Ball TM, Smith WL. Song I, et al. Among authors: smith wl. Biochem Biophys Res Commun. 2001 Dec 14;289(4):869-75. doi: 10.1006/bbrc.2001.6071. Biochem Biophys Res Commun. 2001. PMID: 11735127
The productive conformation of arachidonic acid bound to prostaglandin synthase.
Malkowski MG, Ginell SL, Smith WL, Garavito RM. Malkowski MG, et al. Among authors: smith wl. Science. 2000 Sep 15;289(5486):1933-7. doi: 10.1126/science.289.5486.1933. Science. 2000. PMID: 10988074
Peroxidase activity in prostaglandin endoperoxide H synthase-1 occurs with a neutral histidine proximal heme ligand.
Seibold SA, Cerda JF, Mulichak AM, Song I, Garavito RM, Arakawa T, Smith WL, Babcock GT. Seibold SA, et al. Among authors: smith wl. Biochemistry. 2000 Jun 6;39(22):6616-24. doi: 10.1021/bi0002333. Biochemistry. 2000. PMID: 10828979
Regulation of prostaglandin endoperoxide H synthase-2 expression by 2,3,7,8,-tetrachlorodibenzo-p-dioxin.
Kraemer SA, Arthur KA, Denison MS, Smith WL, DeWitt DL. Kraemer SA, et al. Among authors: smith wl. Arch Biochem Biophys. 1996 Jun 15;330(2):319-28. doi: 10.1006/abbi.1996.0259. Arch Biochem Biophys. 1996. PMID: 8660662
Trp387 and the putative leucine zippers of PGH synthases-1 and -2.
Hsi LC, Tsai AL, Kulmacz RJ, English DG, Siefker AO, Otto JC, Smith WL. Hsi LC, et al. Among authors: smith wl. J Lipid Mediat. 1993 Mar-Apr;6(1-3):131-8. J Lipid Mediat. 1993. PMID: 8357979
Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-inflammatory drugs.
Laneuville O, Breuer DK, Dewitt DL, Hla T, Funk CD, Smith WL. Laneuville O, et al. Among authors: smith wl. J Pharmacol Exp Ther. 1994 Nov;271(2):927-34. J Pharmacol Exp Ther. 1994. PMID: 7965814
An examination of the source of the tyrosyl radical in ovine prostaglandin endoperoxide synthase-1.
Hsi LC, Hoganson CW, Babcock GT, Garavito RM, Smith WL. Hsi LC, et al. Among authors: smith wl. Biochem Biophys Res Commun. 1995 Feb 15;207(2):652-60. doi: 10.1006/bbrc.1995.1237. Biochem Biophys Res Commun. 1995. PMID: 7864856
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