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Phospholipase Cε Modulates Rap1 Activity and the Endothelial Barrier.
DiStefano PV, Smrcka AV, Glading AJ. DiStefano PV, et al. Among authors: smrcka av. PLoS One. 2016 Sep 9;11(9):e0162338. doi: 10.1371/journal.pone.0162338. eCollection 2016. PLoS One. 2016. PMID: 27612188 Free PMC article.
Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.
Smrcka AV, Hepler JR, Brown KO, Sternweis PC. Smrcka AV, et al. Science. 1991 Feb 15;251(4995):804-7. doi: 10.1126/science.1846707. Science. 1991. PMID: 1846707
G proteins in signal transduction: the regulation of phospholipase C.
Sternweis PC, Smrcka AV. Sternweis PC, et al. Among authors: smrcka av. Ciba Found Symp. 1993;176:96-106; discussion 106-11. doi: 10.1002/9780470514450.ch7. Ciba Found Symp. 1993. PMID: 8299429 Review.
Pertussis toxin-sensitive activation of phospholipase C by the C5a and fMet-Leu-Phe receptors.
Jiang H, Kuang Y, Wu Y, Smrcka A, Simon MI, Wu D. Jiang H, et al. Among authors: smrcka a. J Biol Chem. 1996 Jun 7;271(23):13430-4. doi: 10.1074/jbc.271.23.13430. J Biol Chem. 1996. PMID: 8662841
Phospholipase C beta2 association with phospholipid interfaces assessed by fluorescence resonance energy transfer. G protein betagamma subunit-mediated translocation is not required for enzyme activation.
Romoser V, Ball R, Smrcka AV. Romoser V, et al. Among authors: smrcka av. J Biol Chem. 1996 Oct 11;271(41):25071-8. doi: 10.1074/jbc.271.41.25071. J Biol Chem. 1996. PMID: 8810260
Identification of a structural element in phospholipase C beta2 that interacts with G protein betagamma subunits.
Sankaran B, Osterhout J, Wu D, Smrcka AV. Sankaran B, et al. Among authors: smrcka av. J Biol Chem. 1998 Mar 20;273(12):7148-54. doi: 10.1074/jbc.273.12.7148. J Biol Chem. 1998. PMID: 9507029
Genetic alteration of phospholipase C beta3 expression modulates behavioral and cellular responses to mu opioids.
Xie W, Samoriski GM, McLaughlin JP, Romoser VA, Smrcka A, Hinkle PM, Bidlack JM, Gross RA, Jiang H, Wu D. Xie W, et al. Among authors: smrcka a. Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10385-90. doi: 10.1073/pnas.96.18.10385. Proc Natl Acad Sci U S A. 1999. PMID: 10468617 Free PMC article.
Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction.
Li Z, Jiang H, Xie W, Zhang Z, Smrcka AV, Wu D. Li Z, et al. Among authors: smrcka av. Science. 2000 Feb 11;287(5455):1046-9. doi: 10.1126/science.287.5455.1046. Science. 2000. PMID: 10669417
Characterization of a phospholipase C beta 2-binding site near the amino-terminal coiled-coil of G protein beta gamma subunits.
Yoshikawa DM, Bresciano K, Hatwar M, Smrcka AV. Yoshikawa DM, et al. Among authors: smrcka av. J Biol Chem. 2001 Apr 6;276(14):11246-51. doi: 10.1074/jbc.M006073200. Epub 2001 Jan 5. J Biol Chem. 2001. PMID: 11145956
., and Smrcka, A. V. (1998) J. Biol. Chem. 273, 7148-7154), we showed that overlapping peptides, N20K (Asn(564)-Lys(583)) and E20K (Glu(574)-Lys(593)), from the catalytic domain of phospholipase C (PLC) beta2 block Gbetagamma-dependent activation of PLC beta2. ...
., and Smrcka, A. V. (1998) J. Biol. Chem. 273, 7148-7154), we showed that overlapping peptides, N20K (Asn(564)-Lys(583)) and E20K (G …
Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit-binding peptides.
Goubaeva F, Ghosh M, Malik S, Yang J, Hinkle PM, Griendling KK, Neubig RR, Smrcka AV. Goubaeva F, et al. Among authors: smrcka av. J Biol Chem. 2003 May 30;278(22):19634-41. doi: 10.1074/jbc.M300052200. Epub 2003 Mar 20. J Biol Chem. 2003. PMID: 12649269
., and Smrcka, A. V. (2001) EMBO J. 20, 767-776). Here, we created cell-permeating versions of some of these peptides by N-terminal modification with either myristate or the cell permeation sequence from human immunodeficiency virus TAT protein. ...
., and Smrcka, A. V. (2001) EMBO J. 20, 767-776). Here, we created cell-permeating versions of some of these peptides by N-terminal m …
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