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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1888 2
1909 1
1911 1
1922 1
1925 1
1929 1
1939 1
1941 1
1944 1
1945 1
1946 3
1947 3
1948 2
1949 1
1950 5
1951 10
1952 5
1953 3
1954 2
1955 3
1956 1
1957 4
1958 1
1960 4
1961 1
1962 2
1963 4
1964 1
1965 2
1966 5
1967 4
1968 2
1969 5
1970 3
1971 5
1972 2
1973 6
1974 3
1975 10
1976 18
1977 24
1978 12
1979 18
1980 23
1981 29
1982 33
1983 33
1984 41
1985 38
1986 41
1987 47
1988 50
1989 53
1990 43
1991 56
1992 34
1993 59
1994 26
1995 40
1996 38
1997 36
1998 31
1999 31
2000 48
2001 50
2002 45
2003 43
2004 65
2005 59
2006 59
2007 64
2008 61
2009 49
2010 63
2011 56
2012 45
2013 65
2014 84
2015 71
2016 66
2017 68
2018 64
2019 77
2020 97
2021 108
2022 87
2023 74
2024 90
2025 97
2026 53

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2,543 results

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Page 1
Sodium Benzoate-Harmfulness and Potential Use in Therapies for Disorders Related to the Nervous System: A Review.
Walczak-Nowicka ŁJ, Herbet M. Walczak-Nowicka ŁJ, et al. Nutrients. 2022 Apr 2;14(7):1497. doi: 10.3390/nu14071497. Nutrients. 2022. PMID: 35406109 Free PMC article. Review.
One of the compounds known as a preservative with a high safety profile is sodium benzoate. While some studies show that it can be used to treat conditions such as depression, pain, schizophrenia, autism spectrum disorders, and neurodegenerative diseases, others rep …
One of the compounds known as a preservative with a high safety profile is sodium benzoate. While some studies show that it ca …
Sodium Phenylacetate and Sodium Benzoate.
[No authors listed] [No authors listed] 2026 Mar 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2026 Mar 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 41855367 Free Books & Documents. Review.
Sodium phenylacetate and sodium benzoate have not been studied in nursing mothers, but sodium phenylacetate and sodium benzoate injection has been used as a treatment for acute hyperammonemia in pediatric patients in the early neonatal pe …
Sodium phenylacetate and sodium benzoate have not been studied in nursing mothers, but sodium phenylacetate and …
Sodium benzoate for the treatment of hepatic encephalopathy in humans and animals: a systematic review and meta-analysis.
van Zoest D, Gal B, Agha AH, den Hoed CM, Langendonk JG, Wagenmakers MAEM, Peltenburg C. van Zoest D, et al. Eur J Gastroenterol Hepatol. 2025 Apr 1;37(4):488-496. doi: 10.1097/MEG.0000000000002911. Epub 2024 Dec 19. Eur J Gastroenterol Hepatol. 2025. PMID: 39975997 Free PMC article.
No universally accepted guidelines for the treatment of HE exist. Nitrogen scavengers, such as sodium benzoate (SB), have been proven very effective to treat hyperammonemia in patients with urea cycle defects, in acute and chronic settings. ...
No universally accepted guidelines for the treatment of HE exist. Nitrogen scavengers, such as sodium benzoate (SB), have been …
Probiotics derived sodium benzoate improves social behavior of offspring exposed in the maternal immune activation through regulation of histone lysine benzoylation in astrocytes.
Li T, Chen J, Mi K, Lei J, Ning Z, Lu L, Su Z, Zhu Q, Lin M, Wang Y, Wang J, Xu R, Khaib L, Knight R, Hu Z, Liu X. Li T, et al. Mol Psychiatry. 2025 Dec;30(12):5849-5864. doi: 10.1038/s41380-025-03164-0. Epub 2025 Aug 25. Mol Psychiatry. 2025. PMID: 40855005 Free PMC article.
Furthermore, in the MIA-induced ASD mouse model, we demonstrated that supplementation with Lactiplantibacillus plantarum, or its derived sodium benzoate (NaB), mitigates gut dysbiosis, alleviates deficits of social behavior, glutamate-glutamine levels, and neuronal …
Furthermore, in the MIA-induced ASD mouse model, we demonstrated that supplementation with Lactiplantibacillus plantarum, or its derived …
Sodium benzoate-induced pruritus.
Asero R. Asero R. Allergy. 2006 Oct;61(10):1240-1. doi: 10.1111/j.1398-9995.2006.01154.x. Allergy. 2006. PMID: 16942581 No abstract available.
Sodium benzoate treatment decreased amyloid beta peptides and improved cognitive function among patients with Alzheimer's disease: secondary analysis of a randomized clinical trial.
Lin CH, Lane HY. Lin CH, et al. Transl Psychiatry. 2025 Aug 5;15(1):264. doi: 10.1038/s41398-025-03492-3. Transl Psychiatry. 2025. PMID: 40764372 Free PMC article. Clinical Trial.
Previous studies showed that 750-mg/day or 1000-mg/day (but not 500-mg/day) sodium benzoate treatment improved cognitive function in AD patients with excellent safety and that benzoate decreased Abeta burden in an animal AD model. ...Due to its superior safet …
Previous studies showed that 750-mg/day or 1000-mg/day (but not 500-mg/day) sodium benzoate treatment improved cognitive funct …
Sodium benzoate induces pancreatic inflammation and beta cell apoptosis partially via benzoylation.
Li D, Zhang L, Yang P, He Y, Zhou T, Cheng X, Jiang Z, Long Y, Wan Q, Yan P, Gao C, Huang W, Xu Y. Li D, et al. Ecotoxicol Environ Saf. 2024 Jan 15;270:115877. doi: 10.1016/j.ecoenv.2023.115877. Epub 2023 Dec 26. Ecotoxicol Environ Saf. 2024. PMID: 38150747 Free article.
Epigenetics, specifically histone post-translational modification (HPTM) induced by environmental factors, plays a crucial role in the development of diabetes. Sodium benzoate (NAB) is a widely used additive, however, its potential contribution to diabetes has been …
Epigenetics, specifically histone post-translational modification (HPTM) induced by environmental factors, plays a crucial role in the devel …
Efficacy and safety of add-on sodium benzoate, a D-amino acid oxidase inhibitor, in treatment of schizophrenia: A systematic review and meta-analysis.
Seetharam JC, Maiti R, Mishra A, Mishra BR. Seetharam JC, et al. Asian J Psychiatr. 2022 Feb;68:102947. doi: 10.1016/j.ajp.2021.102947. Epub 2021 Nov 30. Asian J Psychiatr. 2022. PMID: 34890931
BACKGROUND: The role of sodium benzoate, an NMDA receptor enhancer, in schizophrenia has been evaluated in a few clinical trials, but results are contradictory and inconclusive. ...CONCLUSION: Sodium benzoate can improve the positive symptoms of schizo …
BACKGROUND: The role of sodium benzoate, an NMDA receptor enhancer, in schizophrenia has been evaluated in a few clinical tria …
Sodium benzoate attenuates 2,8-dihydroxyadenine nephropathy by inhibiting monocyte/macrophage TNF-alpha expression.
Oshima Y, Wakino S, Kanda T, Tajima T, Itoh T, Uchiyama K, Yoshimoto K, Sasabe J, Yasui M, Itoh H. Oshima Y, et al. Sci Rep. 2023 Feb 27;13(1):3331. doi: 10.1038/s41598-023-30056-6. Sci Rep. 2023. PMID: 36849798 Free PMC article.
Sodium benzoate (SB), a known D-amino acid oxidase (DAO) enzyme inhibitor, has an anti-inflammatory effect, although its role in renal damage has not been explored. 2,8-dihydroxyadenine crystal induced chronic kidney disease, in which TNF-alpha is involved in the pa …
Sodium benzoate (SB), a known D-amino acid oxidase (DAO) enzyme inhibitor, has an anti-inflammatory effect, although its role …
Toxicological assessment of sodium benzoate in Drosophila melanogaster.
Asejeje FO, Alade TF, Oyibo A, Abolaji AO. Asejeje FO, et al. J Biochem Mol Toxicol. 2024 Jan;38(1):e23586. doi: 10.1002/jbt.23586. Epub 2023 Nov 20. J Biochem Mol Toxicol. 2024. PMID: 37986221
Sodium benzoate (SB), the sodium salt of benzoic acid, is a food preservative with wide applications in the food, cosmetic and pharmaceutical industries due to its ability to kill many microorganisms effectively. ...
Sodium benzoate (SB), the sodium salt of benzoic acid, is a food preservative with wide applications in the food, cosme …
2,543 results