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Effects of overexpression of copper-zinc and manganese superoxide dismutases, catalase, and thioredoxin reductase genes on longevity in Drosophila melanogaster.

Orr WC, Mockett RJ, Benes JJ, Sohal RS. Orr WC, et al. Among authors: sohal rs. J Biol Chem. 2003 Jul 18;278(29):26418-22. doi: 10.1074/jbc.M303095200. Epub 2003 May 12. J Biol Chem. 2003. PMID: 12743125 Free article.

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Oxidative stress as a causal factor in differentiation and aging: a unifying hypothesis.

Sohal RS, Allen RG. Sohal RS, et al. Exp Gerontol. 1990;25(6):499-522. doi: 10.1016/0531-5565(90)90017-v. Exp Gerontol. 1990. PMID: 2097168 Review.

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Decrease in cytochrome c oxidase reserve capacity diminishes robustness of Drosophila melanogaster and shortens lifespan.

Klichko V, Sohal BH, Radyuk SN, Orr WC, Sohal RS. Klichko V, et al. Among authors: sohal rs. Biochem J. 2014 Apr 1;459(1):127-35. doi: 10.1042/BJ20131370. Biochem J. 2014. PMID: 24444354

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Involvement of redox state in the aging of Drosophila melanogaster.

Orr WC, Radyuk SN, Sohal RS. Orr WC, et al. Among authors: sohal rs. Antioxid Redox Signal. 2013 Sep 10;19(8):788-803. doi: 10.1089/ars.2012.5002. Epub 2013 Apr 6. Antioxid Redox Signal. 2013. PMID: 23458359 Free PMC article. Review.

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Mitochondrial peroxiredoxins are critical for the maintenance of redox state and the survival of adult Drosophila.

Radyuk SN, Rebrin I, Klichko VI, Sohal BH, Michalak K, Benes J, Sohal RS, Orr WC. Radyuk SN, et al. Among authors: sohal rs, sohal bh. Free Radic Biol Med. 2010 Dec 15;49(12):1892-902. doi: 10.1016/j.freeradbiomed.2010.09.014. Epub 2010 Oct 19. Free Radic Biol Med. 2010. PMID: 20869434 Free PMC article.

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Peroxiredoxin 5 confers protection against oxidative stress and apoptosis and also promotes longevity in Drosophila.

Radyuk SN, Michalak K, Klichko VI, Benes J, Rebrin I, Sohal RS, Orr WC. Radyuk SN, et al. Among authors: sohal rs. Biochem J. 2009 Apr 15;419(2):437-45. doi: 10.1042/BJ20082003. Biochem J. 2009. PMID: 19128239 Free PMC article.

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The catalytic subunit of Drosophila glutamate-cysteine ligase is a nucleocytoplasmic shuttling protein.

Radyuk SN, Rebrin I, Luchak JM, Michalak K, Klichko VI, Sohal RS, Orr WC. Radyuk SN, et al. Among authors: sohal rs. J Biol Chem. 2009 Jan 23;284(4):2266-74. doi: 10.1074/jbc.M805913200. Epub 2008 Nov 26. J Biol Chem. 2009. PMID: 19036725 Free PMC article.

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Overexpression of glucose-6-phosphate dehydrogenase extends the life span of Drosophila melanogaster.

Legan SK, Rebrin I, Mockett RJ, Radyuk SN, Klichko VI, Sohal RS, Orr WC. Legan SK, et al. Among authors: sohal rs. J Biol Chem. 2008 Nov 21;283(47):32492-9. doi: 10.1074/jbc.M805832200. Epub 2008 Sep 22. J Biol Chem. 2008. PMID: 18809674 Free PMC article.

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Modulating longevity in Drosophila by over- and underexpression of glutamate-cysteine ligase.

Luchak JM, Prabhudesai L, Sohal RS, Radyuk SN, Orr WC. Luchak JM, et al. Among authors: sohal rs. Ann N Y Acad Sci. 2007 Nov;1119:260-73. doi: 10.1196/annals.1404.000. Ann N Y Acad Sci. 2007. PMID: 18056974

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Effects of ectopic expression of Drosophila DNA glycosylases dOgg1 and RpS3 in mitochondria.

Radyuk SN, Michalak K, Rebrin I, Sohal RS, Orr WC. Radyuk SN, et al. Among authors: sohal rs. Free Radic Biol Med. 2006 Sep 1;41(5):757-64. doi: 10.1016/j.freeradbiomed.2006.05.021. Epub 2006 May 26. Free Radic Biol Med. 2006. PMID: 16895796 Free PMC article.

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