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Expression of the transcriptional repressor Gfi-1 is regulated by C/EBP{alpha} and is involved in its proliferation and colony formation-inhibitory effects in p210BCR/ABL-expressing cells.
Lidonnici MR, Audia A, Soliera AR, Prisco M, Ferrari-Amorotti G, Waldron T, Donato N, Zhang Y, Martinez RV, Holyoake TL, Calabretta B. Lidonnici MR, et al. Among authors: soliera ar. Cancer Res. 2010 Oct 15;70(20):7949-59. doi: 10.1158/0008-5472.CAN-10-1667. Epub 2010 Oct 5. Cancer Res. 2010. PMID: 20924107 Free PMC article.
The biological effects of C/EBPalpha in K562 cells depend on the potency of the N-terminal regulatory region, not on specificity of the DNA binding domain.
Ferrari-Amorotti G, Mariani SA, Novi C, Cattelani S, Pecorari L, Corradini F, Soliera AR, Manzotti G, Fragliasso V, Zhang Y, Martinez RV, Lam EW, Guerzoni C, Calabretta B. Ferrari-Amorotti G, et al. Among authors: soliera ar. J Biol Chem. 2010 Oct 1;285(40):30837-50. doi: 10.1074/jbc.M110.128272. Epub 2010 Jul 20. J Biol Chem. 2010. PMID: 20659895 Free PMC article.
Phosphorylation of serine 21 modulates the proliferation inhibitory more than the differentiation inducing effects of C/EBPα in K562 cells.
Fragliasso V, Chiodo Y, Ferrari-Amorotti G, Soliera AR, Manzotti G, Cattelani S, Candini O, Grisendi G, Vergalli J, Mariani SA, Guerzoni C, Calabretta B. Fragliasso V, et al. Among authors: soliera ar. J Cell Biochem. 2012 May;113(5):1704-13. doi: 10.1002/jcb.24040. J Cell Biochem. 2012. PMID: 22212957 Free PMC article.
Expression of p89(c-Mybex9b), an alternatively spliced form of c-Myb, is required for proliferation and survival of p210BCR/ABL-expressing cells.
Manzotti G, Mariani SA, Corradini F, Bussolari R, Cesi V, Vergalli J, Ferrari-Amorotti G, Fragliasso V, Soliera AR, Cattelani S, Raschellà G, Holyoake TL, Calabretta B. Manzotti G, et al. Among authors: soliera ar. Blood Cancer J. 2012 May;2(5):e71. doi: 10.1038/bcj.2012.16. Epub 2012 May 11. Blood Cancer J. 2012. PMID: 22829973 Free PMC article.
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.
Bellodi C, Lidonnici MR, Hamilton A, Helgason GV, Soliera AR, Ronchetti M, Galavotti S, Young KW, Selmi T, Yacobi R, Van Etten RA, Donato N, Hunter A, Dinsdale D, Tirrò E, Vigneri P, Nicotera P, Dyer MJ, Holyoake T, Salomoni P, Calabretta B. Bellodi C, et al. Among authors: soliera ar. J Clin Invest. 2009 May;119(5):1109-23. doi: 10.1172/JCI35660. Epub 2009 Apr 13. J Clin Invest. 2009. PMID: 19363292 Free PMC article.
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