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Reactive oxygen species directly modify sodium-calcium exchanger activity in a splice variant-dependent manner.
Soliman D, Hamming KS, Matemisz LC, Light PE. Soliman D, et al. J Mol Cell Cardiol. 2009 Nov;47(5):595-602. doi: 10.1016/j.yjmcc.2009.05.011. Epub 2009 May 28. J Mol Cell Cardiol. 2009. PMID: 19481548
Carbonic anhydrase inhibition prevents and reverts cardiomyocyte hypertrophy.
Alvarez BV, Johnson DE, Sowah D, Soliman D, Light PE, Xia Y, Karmazyn M, Casey JR. Alvarez BV, et al. Among authors: soliman d. J Physiol. 2007 Feb 15;579(Pt 1):127-45. doi: 10.1113/jphysiol.2006.123638. Epub 2006 Nov 23. J Physiol. 2007. PMID: 17124262 Free PMC article.
Late sodium current inhibition alone with ranolazine is sufficient to reduce ischemia- and cardiac glycoside-induced calcium overload and contractile dysfunction mediated by reverse-mode sodium/calcium exchange.
Soliman D, Wang L, Hamming KS, Yang W, Fatehi M, Carter CC, Clanachan AS, Light PE. Soliman D, et al. J Pharmacol Exp Ther. 2012 Nov;343(2):325-32. doi: 10.1124/jpet.112.196949. Epub 2012 Aug 9. J Pharmacol Exp Ther. 2012. PMID: 22879384
The ATP-sensitive K(+) channel ABCC8 S1369A type 2 diabetes risk variant increases MgATPase activity.
Fatehi M, Raja M, Carter C, Soliman D, Holt A, Light PE. Fatehi M, et al. Among authors: soliman d. Diabetes. 2012 Jan;61(1):241-9. doi: 10.2337/db11-0371. Diabetes. 2012. PMID: 22187380 Free PMC article.
Inhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion.
Hamming KS, Soliman D, Webster NJ, Searle GJ, Matemisz LC, Liknes DA, Dai XQ, Pulinilkunnil T, Riedel MJ, Dyck JR, Macdonald PE, Light PE. Hamming KS, et al. Among authors: soliman d. Diabetes. 2010 Jul;59(7):1686-93. doi: 10.2337/db09-0630. Epub 2010 Apr 22. Diabetes. 2010. PMID: 20413506 Free PMC article.
Coexpression of the type 2 diabetes susceptibility gene variants KCNJ11 E23K and ABCC8 S1369A alter the ATP and sulfonylurea sensitivities of the ATP-sensitive K(+) channel.
Hamming KS, Soliman D, Matemisz LC, Niazi O, Lang Y, Gloyn AL, Light PE. Hamming KS, et al. Among authors: soliman d. Diabetes. 2009 Oct;58(10):2419-24. doi: 10.2337/db09-0143. Epub 2009 Jul 8. Diabetes. 2009. PMID: 19587354 Free PMC article.
Splice variant-dependent regulation of beta-cell sodium-calcium exchange by acyl-coenzyme As.
Hamming KS, Riedel MJ, Soliman D, Matemisz LC, Webster NJ, Searle GJ, MacDonald PE, Light PE. Hamming KS, et al. Among authors: soliman d. Mol Endocrinol. 2008 Oct;22(10):2293-306. doi: 10.1210/me.2008-0053. Epub 2008 Jul 17. Mol Endocrinol. 2008. PMID: 18635667 Free PMC article.
Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility.
Nagendran J, Archer SL, Soliman D, Gurtu V, Moudgil R, Haromy A, St Aubin C, Webster L, Rebeyka IM, Ross DB, Light PE, Dyck JR, Michelakis ED. Nagendran J, et al. Among authors: soliman d. Circulation. 2007 Jul 17;116(3):238-48. doi: 10.1161/CIRCULATIONAHA.106.655266. Epub 2007 Jul 2. Circulation. 2007. PMID: 17606845
Role of cytokines in alveolar macrophage accessory cell function in HIV-infected individuals.
Twigg HL 3rd, Iwamoto GK, Soliman DM. Twigg HL 3rd, et al. Among authors: soliman dm. J Immunol. 1992 Aug 15;149(4):1462-9. J Immunol. 1992. PMID: 1500725
Lymphocytic alveolitis, bronchoalveolar lavage viral load, and outcome in human immunodeficiency virus infection.
Twigg HL, Soliman DM, Day RB, Knox KS, Anderson RJ, Wilkes DS, Schnizlein-Bick CT. Twigg HL, et al. Among authors: soliman dm. Am J Respir Crit Care Med. 1999 May;159(5 Pt 1):1439-44. doi: 10.1164/ajrccm.159.5.9808031. Am J Respir Crit Care Med. 1999. PMID: 10228108
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