Solit DB - Search Results

1

Perturbation biology: inferring signaling networks in cellular systems.

Molinelli EJ, Korkut A, Wang W, Miller ML, Gauthier NP, Jing X, Kaushik P, He Q, Mills G, Solit DB, Pratilas CA, Weigt M, Braunstein A, Pagnani A, Zecchina R, Sander C. Molinelli EJ, et al. Among authors: solit db. PLoS Comput Biol. 2013;9(12):e1003290. doi: 10.1371/journal.pcbi.1003290. Epub 2013 Dec 19. PLoS Comput Biol. 2013. PMID: 24367245 Free PMC article.

2

New efficient synthesis of resorcinylic macrolides via ynolides: establishment of cycloproparadicicol as synthetically feasible preclinical anticancer agent based on Hsp90 as the target.

Yang ZQ, Geng X, Solit D, Pratilas CA, Rosen N, Danishefsky SJ. Yang ZQ, et al. J Am Chem Soc. 2004 Jun 30;126(25):7881-9. doi: 10.1021/ja0484348. J Am Chem Soc. 2004. PMID: 15212536

3

BRAF mutation predicts sensitivity to MEK inhibition.

Solit DB, Garraway LA, Pratilas CA, Sawai A, Getz G, Basso A, Ye Q, Lobo JM, She Y, Osman I, Golub TR, Sebolt-Leopold J, Sellers WR, Rosen N. Solit DB, et al. Nature. 2006 Jan 19;439(7074):358-62. doi: 10.1038/nature04304. Epub 2005 Nov 6. Nature. 2006. PMID: 16273091 Free PMC article.

4

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt.

O'Reilly KE, Rojo F, She QB, Solit D, Mills GB, Smith D, Lane H, Hofmann F, Hicklin DJ, Ludwig DL, Baselga J, Rosen N. O'Reilly KE, et al. Cancer Res. 2006 Feb 1;66(3):1500-8. doi: 10.1158/0008-5472.CAN-05-2925. Cancer Res. 2006. PMID: 16452206 Free PMC article.

5

3'-deoxy-3'-[18F]fluorothymidine positron emission tomography is a sensitive method for imaging the response of BRAF-dependent tumors to MEK inhibition.

Solit DB, Santos E, Pratilas CA, Lobo J, Moroz M, Cai S, Blasberg R, Sebolt-Leopold J, Larson S, Rosen N. Solit DB, et al. Cancer Res. 2007 Dec 1;67(23):11463-9. doi: 10.1158/0008-5472.CAN-07-2976. Cancer Res. 2007. PMID: 18056475 Free PMC article.

6

BRAFV600E mutation is associated with preferential sensitivity to mitogen-activated protein kinase kinase inhibition in thyroid cancer cell lines.

Leboeuf R, Baumgartner JE, Benezra M, Malaguarnera R, Solit D, Pratilas CA, Rosen N, Knauf JA, Fagin JA. Leboeuf R, et al. J Clin Endocrinol Metab. 2008 Jun;93(6):2194-201. doi: 10.1210/jc.2007-2825. Epub 2008 Apr 1. J Clin Endocrinol Metab. 2008. PMID: 18381570 Free PMC article.

7

Therapeutic strategies for targeting BRAF in human cancer.

Pratilas CA, Solit DB. Pratilas CA, et al. Among authors: solit db. Rev Recent Clin Trials. 2007 May;2(2):121-34. doi: 10.2174/157488707780599393. Rev Recent Clin Trials. 2007. PMID: 18473997 Review.

8

Genetic predictors of MEK dependence in non-small cell lung cancer.

Pratilas CA, Hanrahan AJ, Halilovic E, Persaud Y, Soh J, Chitale D, Shigematsu H, Yamamoto H, Sawai A, Janakiraman M, Taylor BS, Pao W, Toyooka S, Ladanyi M, Gazdar A, Rosen N, Solit DB. Pratilas CA, et al. Among authors: solit db. Cancer Res. 2008 Nov 15;68(22):9375-83. doi: 10.1158/0008-5472.CAN-08-2223. Cancer Res. 2008. PMID: 19010912 Free PMC article.

9

(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway.

Pratilas CA, Taylor BS, Ye Q, Viale A, Sander C, Solit DB, Rosen N. Pratilas CA, et al. Among authors: solit db. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4519-24. doi: 10.1073/pnas.0900780106. Epub 2009 Feb 27. Proc Natl Acad Sci U S A. 2009. PMID: 19251651 Free PMC article.

10

Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies.

Veeriah S, Taylor BS, Meng S, Fang F, Yilmaz E, Vivanco I, Janakiraman M, Schultz N, Hanrahan AJ, Pao W, Ladanyi M, Sander C, Heguy A, Holland EC, Paty PB, Mischel PS, Liau L, Cloughesy TF, Mellinghoff IK, Solit DB, Chan TA. Veeriah S, et al. Among authors: solit db. Nat Genet. 2010 Jan;42(1):77-82. doi: 10.1038/ng.491. Epub 2009 Nov 29. Nat Genet. 2010. PMID: 19946270 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

374 results

Search Page