Solomon VR - Search Results

1

Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies.

Solomon VR, Lee H. Solomon VR, et al. Eur J Pharmacol. 2009 Dec 25;625(1-3):220-33. doi: 10.1016/j.ejphar.2009.06.063. Epub 2009 Oct 15. Eur J Pharmacol. 2009. PMID: 19836374 Review.

2

Design and synthesis of novel quinacrine-[1,3]-thiazinan-4-one hybrids for their anti-breast cancer activity.

Solomon VR, Pundir S, Le HT, Lee H. Solomon VR, et al. Eur J Med Chem. 2018 Jan 1;143:1028-1038. doi: 10.1016/j.ejmech.2017.11.097. Eur J Med Chem. 2018. PMID: 29232580

3

Design, synthesis and characterization of novel quinacrine analogs that preferentially kill cancer over non-cancer cells through the down-regulation of Bcl-2 and up-regulation of Bax and Bad.

Solomon VR, Almnayan D, Lee H. Solomon VR, et al. Eur J Med Chem. 2017 Sep 8;137:156-166. doi: 10.1016/j.ejmech.2017.05.052. Epub 2017 May 27. Eur J Med Chem. 2017. PMID: 28586716

4

VR23: A Quinoline-Sulfonyl Hybrid Proteasome Inhibitor That Selectively Kills Cancer via Cyclin E-Mediated Centrosome Amplification.

Pundir S, Vu HY, Solomon VR, McClure R, Lee H. Pundir S, et al. Among authors: solomon vr. Cancer Res. 2015 Oct 1;75(19):4164-75. doi: 10.1158/0008-5472.CAN-14-3370. Epub 2015 Aug 3. Cancer Res. 2015. PMID: 26238784

5

The potential of quinoline derivatives for the treatment of Toxoplasma gondii infection.

Kadri D, Crater AK, Lee H, Solomon VR, Ananvoranich S. Kadri D, et al. Among authors: solomon vr. Exp Parasitol. 2014 Oct;145:135-44. doi: 10.1016/j.exppara.2014.08.008. Epub 2014 Aug 13. Exp Parasitol. 2014. PMID: 25128801

6

Anti-breast cancer activity of heteroaryl chalcone derivatives.

Solomon VR, Lee H. Solomon VR, et al. Biomed Pharmacother. 2012 Apr;66(3):213-20. doi: 10.1016/j.biopha.2011.11.013. Epub 2011 Dec 31. Biomed Pharmacother. 2012. PMID: 22440895

7

Design and synthesis of anti-breast cancer agents from 4-piperazinylquinoline: a hybrid pharmacophore approach.

Solomon VR, Hu C, Lee H. Solomon VR, et al. Bioorg Med Chem. 2010 Feb 15;18(4):1563-72. doi: 10.1016/j.bmc.2010.01.001. Epub 2010 Jan 11. Bioorg Med Chem. 2010. PMID: 20106668

8

Hybrid pharmacophore design and synthesis of isatin-benzothiazole analogs for their anti-breast cancer activity.

Solomon VR, Hu C, Lee H. Solomon VR, et al. Bioorg Med Chem. 2009 Nov 1;17(21):7585-92. doi: 10.1016/j.bmc.2009.08.068. Epub 2009 Sep 15. Bioorg Med Chem. 2009. PMID: 19804979

9

Synthesis and in vitro cytotoxicity evaluation of 4-aminoquinoline derivatives.

Zhang H, Solomon VR, Hu C, Ulibarri G, Lee H. Zhang H, et al. Among authors: solomon vr. Biomed Pharmacother. 2008 Feb;62(2):65-9. doi: 10.1016/j.biopha.2007.04.007. Epub 2007 May 24. Biomed Pharmacother. 2008. PMID: 17555912 Free PMC article.

10

The efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquine.

Hu C, Solomon VR, Ulibarri G, Lee H. Hu C, et al. Among authors: solomon vr. Bioorg Med Chem. 2008 Sep 1;16(17):7888-93. doi: 10.1016/j.bmc.2008.07.076. Epub 2008 Jul 29. Bioorg Med Chem. 2008. PMID: 18691894

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