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Solubility and bioavailability of stabilized amorphous calcium carbonate.
Meiron OE, Bar-David E, Aflalo ED, Shechter A, Stepensky D, Berman A, Sagi A. Meiron OE, et al. J Bone Miner Res. 2011 Feb;26(2):364-72. doi: 10.1002/jbmr.196. Epub 2010 Aug 5. J Bone Miner Res. 2011. PMID: 20690187 Free article.
Recent technology allowing the production of a stable amorphous calcium carbonate (ACC) now enables a bioavailability analysis of this unique form of calcium. ...This study demonstrates the enhanced solubility and bioavailability o …
Recent technology allowing the production of a stable amorphous calcium carbonate (ACC) now enables a bioavailabilit
Mesoporous calcium carbonate as a phase stabilizer of amorphous celecoxib--an approach to increase the bioavailability of poorly soluble pharmaceutical substances.
Forsgren J, Andersson M, Nilsson P, Mihranyan A. Forsgren J, et al. Adv Healthc Mater. 2013 Nov;2(11):1469-76. doi: 10.1002/adhm.201200391. Epub 2013 May 23. Adv Healthc Mater. 2013. PMID: 23703752
The bioavailability of crystalline pharmaceutical substances is often limited by their poor aqueous solubility but it can be improved by formulating the active substance in the amorphous state that is featured with a higher apparent solubility. ...This …
The bioavailability of crystalline pharmaceutical substances is often limited by their poor aqueous solubility but it can be i …
Hydroxypropyl-β-cyclodextrin functionalized calcium carbonate microparticles as a potential carrier for enhancing oral delivery of water-insoluble drugs.
Zhang L, Zhu W, Lin Q, Han J, Jiang L, Zhang Y. Zhang L, et al. Int J Nanomedicine. 2015 Apr 30;10:3291-302. doi: 10.2147/IJN.S78814. eCollection 2015. Int J Nanomedicine. 2015. PMID: 25995635 Free PMC article.
The objective of the present study was to demonstrate that a novel hydroxypropyl-β-cyclodextrin functionalized calcium carbonate (HP-β-CD/CC) based amorphous solid dispersion (ASD) can be used to increase the solubility and oral bioavailability
The objective of the present study was to demonstrate that a novel hydroxypropyl-β-cyclodextrin functionalized calcium carbonate
In situ molecular NMR picture of bioavailable calcium stabilized as amorphous CaCO₃ biomineral in crayfish gastroliths.
Akiva-Tal A, Kababya S, Balazs YS, Glazer L, Berman A, Sagi A, Schmidt A. Akiva-Tal A, et al. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14763-8. doi: 10.1073/pnas.1102608108. Epub 2011 Aug 22. Proc Natl Acad Sci U S A. 2011. PMID: 21873244 Free PMC article.
Bioavailable calcium is maintained by some crustaceans, in particular freshwater crayfish, by stabilizing amorphous calcium carbonate (ACC) within reservoir organs--gastroliths, readily providing the Ca(2+) needed to build a new exoskelet
Bioavailable calcium is maintained by some crustaceans, in particular freshwater crayfish, by stabilizing amorphous
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