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Page 1
Did you mean homatropine (321 results)?
Efficacy and Safety of Weekly Somatrogon vs Daily Somatropin in Children With Growth Hormone Deficiency: A Phase 3 Study.
Deal CL, Steelman J, Vlachopapadopoulou E, Stawerska R, Silverman LA, Phillip M, Kim HS, Ko C, Malievskiy O, Cara JF, Roland CL, Taylor CT, Valluri SR, Wajnrajch MP, Pastrak A, Miller BS. Deal CL, et al. J Clin Endocrinol Metab. 2022 Jun 16;107(7):e2717-e2728. doi: 10.1210/clinem/dgac220. J Clin Endocrinol Metab. 2022. PMID: 35405011 Free PMC article. Clinical Trial.
CONTEXT: Somatrogon is a long-acting recombinant human growth hormone (rhGH) in development for once-weekly treatment of children with growth hormone deficiency (GHD). ...A total of 228 prepubertal children (boys aged 3-11 years, girls aged 3-10 …
CONTEXT: Somatrogon is a long-acting recombinant human growth hormone (rhGH) in development for once-weekly treatment o …
Somatropin (Zorbtive): in short bowel syndrome.
Keating GM, Wellington K. Keating GM, et al. Drugs. 2004;64(12):1375-81; discussion 1382-3. doi: 10.2165/00003495-200464120-00008. Drugs. 2004. PMID: 15200350 Review.
A somatropin preparation (Zorbtive) produced by recombinant DNA technology has been evaluated in patients with short bowel syndrome. Somatropin is thought to enhance intestinal adaptation in this condition through direct or indirect effects on the intestine. ...
A somatropin preparation (Zorbtive) produced by recombinant DNA technology has been evaluated in patients with short bowel syndrome. …
Somatropin and glucose homeostasis: considerations for patient management.
Jørgensen JO, Nørrelund H, Conceicao F, Møller N, Christiansen JS. Jørgensen JO, et al. Treat Endocrinol. 2002;1(4):229-34. doi: 10.2165/00024677-200201040-00004. Treat Endocrinol. 2002. PMID: 15799216 Review.
Accordingly, active acromegaly is characterized by insulin resistance at the hepatic and muscular level, whereas children with growth hormone (GH) deficiency are insulin hypersensitive and prone to developing fasting hypoglycemia. ...Subcutaneous somatropin t …
Accordingly, active acromegaly is characterized by insulin resistance at the hepatic and muscular level, whereas children with growth
Somatropin therapy in adults with Prader-Willi syndrome.
Höybye C, Thorén M. Höybye C, et al. Treat Endocrinol. 2004;3(3):153-60. doi: 10.2165/00024677-200403030-00003. Treat Endocrinol. 2004. PMID: 16026111 Review.
Prader-Willi syndrome is a complex genetic disorder with a characteristic cognitive, behavioral, and endocrinologic phenotype. Obesity, partial growth hormone (GH) secretion, and hypogonadism are common. Results of several somatropin (GH therapy) studies in c …
Prader-Willi syndrome is a complex genetic disorder with a characteristic cognitive, behavioral, and endocrinologic phenotype. Obesity, part …
Somatropin therapy in italian adults with growth hormone deficiency.
Pricci F, Rotondi D, Villa M, Valerio A, Agazio E, Roazzi P. Pricci F, et al. BMC Endocr Disord. 2022 Mar 3;22(1):52. doi: 10.1186/s12902-022-00960-5. BMC Endocr Disord. 2022. PMID: 35241041 Free PMC article.
Growth Hormone (GH) replacement therapy has beneficial effects entailing a chronic and expensive use. ...In Italy, the epidemiological surveillance on somatropin therapy is entrusted to the National Register of Growth Hormone Therapy (Registro N
Growth Hormone (GH) replacement therapy has beneficial effects entailing a chronic and expensive use. ...In Italy, the epidemi
[Somatropin and final height in Mexican paediatric population with growth hormone deficiency].
Rivera-Hernández A, Sánchez-García F, Zurita-Cruz J, Balcázar-Hernández L. Rivera-Hernández A, et al. Andes Pediatr. 2022 Aug;93(4):496-503. doi: 10.32641/andespediatr.v93i4.3763. Andes Pediatr. 2022. PMID: 37906847 Free article. Spanish.
Treatment with recombinant growth hormone, or somatropin, increases linear growth and is effective in improving final height in children with isolated growth hormone deficiency (IGHD), however, the available information of these results i …
Treatment with recombinant growth hormone, or somatropin, increases linear growth and is effective in improving …
Spotlight on mammalian cell-derived somatropin in HIV-associated wasting.
Goldsmith DR, Wagstaff AJ. Goldsmith DR, et al. BioDrugs. 2006;20(3):191-2. doi: 10.2165/00063030-200620030-00006. BioDrugs. 2006. PMID: 16724867 Review.
Loss of body cell mass, a component of lean body mass, is associated with decreased survival. Somatropin (recombinant human growth hormone) derived from mammalian cells (Serostim) is the only US FDA-approved treatment indicated to increase lean body ma …
Loss of body cell mass, a component of lean body mass, is associated with decreased survival. Somatropin (recombinant human
The role of somatropin therapy in children with Noonan syndrome.
Kelnar CJ. Kelnar CJ. Treat Endocrinol. 2003;2(3):165-72. doi: 10.2165/00024677-200302030-00003. Treat Endocrinol. 2003. PMID: 15966565 Review.
Available evidence suggests that there may be disturbance of the growth hormone/insulin-like growth factor axis in Noonan syndrome and that somatropin (growth hormone therapy) dose-dependently improves vertical growth in the short …
Available evidence suggests that there may be disturbance of the growth hormone/insulin-like growth factor axis in Noon …
Weekly Lonapegsomatropin in Treatment-Naive Children With Growth Hormone Deficiency: The Phase 3 heiGHt Trial.
Thornton PS, Maniatis AK, Aghajanova E, Chertok E, Vlachopapadopoulou E, Lin Z, Song W, Christoffersen ED, Breinholt VM, Kovalenko T, Giorgadze E, Korpal-Szczyrska M, Hofman PL, Karpf DB, Shu AD, Beckert M. Thornton PS, et al. J Clin Endocrinol Metab. 2021 Oct 21;106(11):3184-3195. doi: 10.1210/clinem/dgab529. J Clin Endocrinol Metab. 2021. PMID: 34272849 Free PMC article. Clinical Trial.
CONTEXT: For children with growth hormone deficiency (GHD), treatment burden with daily somatropin injections [human growth hormone (hGH)] is high, which may lead to poor adherence and suboptimal overall treatment outcomes. ...RESULTS: Le …
CONTEXT: For children with growth hormone deficiency (GHD), treatment burden with daily somatropin injections [human
Safety and Efficacy of Pediatric Growth Hormone Therapy: Results From the Full KIGS Cohort.
Maghnie M, Ranke MB, Geffner ME, Vlachopapadopoulou E, Ibáñez L, Carlsson M, Cutfield W, Rooman R, Gomez R, Wajnrajch MP, Linglart A, Stawerska R, Clayton PE, Darendeliler F, Hokken-Koelega ACS, Horikawa R, Tanaka T, Dörr HG, Albertsson-Wikland K, Polak M, Grimberg A. Maghnie M, et al. J Clin Endocrinol Metab. 2022 Nov 25;107(12):3287-3301. doi: 10.1210/clinem/dgac517. J Clin Endocrinol Metab. 2022. PMID: 36102184 Free PMC article.
CONTEXT: The Kabi/Pfizer International Growth Database (KIGS) is a large, international database (1987-2012) of children treated with recombinant human growth hormone (rhGH) in real-world settings. ...METHODS: Data were collected by investigators from …
CONTEXT: The Kabi/Pfizer International Growth Database (KIGS) is a large, international database (1987-2012) of children treated with …
53,839 results
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