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Some experiences and opportunities for big data in translational research.
Chute CG, Ullman-Cullere M, Wood GM, Lin SM, He M, Pathak J. Chute CG, et al. Genet Med. 2013 Oct;15(10):802-9. doi: 10.1038/gim.2013.121. Epub 2013 Sep 5. Genet Med. 2013. PMID: 24008998 Free PMC article. Review.
Translational research in the present day increasingly embraces new biomedical discovery in this data-intensive world, thus entering the domain of "big data." The Electronic Medical Records and Genomics consortium has taught us many lesso
Translational research in the present day increasingly embraces new biomedical discovery in this data-intensive
Fit-for-Purpose Biometric Monitoring Technologies: Leveraging the Laboratory Biomarker Experience.
Godfrey A, Vandendriessche B, Bakker JP, Fitzer-Attas C, Gujar N, Hobbs M, Liu Q, Northcott CA, Parks V, Wood WA, Zipunnikov V, Wagner JA, Izmailova ES. Godfrey A, et al. Clin Transl Sci. 2021 Jan;14(1):62-74. doi: 10.1111/cts.12865. Epub 2020 Aug 25. Clin Transl Sci. 2021. PMID: 32770726 Free PMC article. Review.
Both categories share common features, including goals and roles in biomedical research, definitions, and many elements of the biomarker qualification framework. ...Novel methods to handle large volumes of data, as well as security and data rights requ …
Both categories share common features, including goals and roles in biomedical research, definitions, and many elements of the …
Identifying Frameworks for Validation and Monitoring of Consensual Behavioral Intervention Technologies: Narrative Review.
Carbonnel F, Ninot G. Carbonnel F, et al. J Med Internet Res. 2019 Oct 16;21(10):e13606. doi: 10.2196/13606. J Med Internet Res. 2019. PMID: 31621638 Free PMC article. Review.
The review items included the following: name, publication year, name of the creator (ie, first author), country, funding organization, health focus, target group, and design (ie, linear, iterative, evolutive, and/or concurrent). The frameworks were then categorized based on (1) …
The review items included the following: name, publication year, name of the creator (ie, first author), country, funding organization, heal …
Centering inclusivity in the design of online conferences-An OHBM-Open Science perspective.
Levitis E, van Praag CDG, Gau R, Heunis S, DuPre E, Kiar G, Bottenhorn KL, Glatard T, Nikolaidis A, Whitaker KJ, Mancini M, Niso G, Afyouni S, Alonso-Ortiz E, Appelhoff S, Arnatkeviciute A, Atay SM, Auer T, Baracchini G, Bayer JMM, Beauvais MJS, Bijsterbosch JD, Bilgin IP, Bollmann S, Bollmann S, Botvinik-Nezer R, Bright MG, Calhoun VD, Chen X, Chopra S, Chuan-Peng H, Close TG, Cookson SL, Craddock RC, De La Vega A, De Leener B, Demeter DV, Di Maio P, Dickie EW, Eickhoff SB, Esteban O, Finc K, Frigo M, Ganesan S, Ganz M, Garner KG, Garza-Villarreal EA, Gonzalez-Escamilla G, Goswami R, Griffiths JD, Grootswagers T, Guay S, Guest O, Handwerker DA, Herholz P, Heuer K, Huijser DC, Iacovella V, Joseph MJE, Karakuzu A, Keator DB, Kobeleva X, Kumar M, Laird AR, Larson-Prior LJ, Lautarescu A, Lazari A, Legarreta JH, Li XY, Lv J, Mansour L S, Meunier D, Moraczewski D, Nandi T, Nastase SA, Nau M, Noble S, Norgaard M, Obungoloch J, Oostenveld R, Orchard ER, Pinho AL, Poldrack RA, Qiu A, Raamana PR, Rokem A, Rutherford S, Sharan M, Shaw TB, Syeda WT, Testerman MM, Toro R, Valk SL, Van Den Bossche S, Varoquaux G, Váša F, Veldsman M, Vohryzek J, Wagner AS, Walsh RJ, White T, Wong FT, Xie X, Yan… See abstract for full author list ➔ Levitis E, et al. Gigascience. 2021 Aug 20;10(8):giab051. doi: 10.1093/gigascience/giab051. Gigascience. 2021. PMID: 34414422 Free PMC article.
A number of studies have outlined how moving online made it possible to gather a more global community and has increased opportunities for individuals with various constraints, e.g., caregiving responsibilities. ...Here, we draw from the literature and from our own expe
A number of studies have outlined how moving online made it possible to gather a more global community and has increased opportunities
Exploring variation in the performance of planned birth: A mixed method study.
Dominiek C, Amanda H, Georgina C, Repon P, Angela M, Teena C, Donnolley N. Dominiek C, et al. Midwifery. 2021 Jul;98:102988. doi: 10.1016/j.midw.2021.102988. Epub 2021 Mar 15. Midwifery. 2021. PMID: 33765483
The aim of this study was to map the variation in IOL and planned CS at eight Australian hospitals, and understand why variation occurs from the perspective of clinicians at these hospitals. Our ultimate aim was to identify opportunities for improvement as evidenced by hos …
The aim of this study was to map the variation in IOL and planned CS at eight Australian hospitals, and understand why variation occurs from …
Translating the therapeutic potential of neurotrophic factors to clinical 'proof of concept': a personal saga achieving a career-long quest.
Bartus RT. Bartus RT. Neurobiol Dis. 2012 Nov;48(2):153-78. doi: 10.1016/j.nbd.2012.04.004. Epub 2012 Apr 16. Neurobiol Dis. 2012. PMID: 22525569 Review.
This paper reviews the development of CERE-120, starting historically with the long-standing interest in the therapeutic potential of neurotrophic factors and continuing with selective accounts of past efforts to translate their potential to the clinic, eventually leading to the …
This paper reviews the development of CERE-120, starting historically with the long-standing interest in the therapeutic potential of neurot …
Broad-scale informed consent: A survey of the CTSA landscape.
Chandler R, Brady KT, Jerome RN, Eder M, Rothwell E, Brownley KA, Harris PA. Chandler R, et al. J Clin Transl Sci. 2019 Sep 23;3(5):253-260. doi: 10.1017/cts.2019.397. eCollection 2019 Oct. J Clin Transl Sci. 2019. PMID: 31660250 Free PMC article.
INTRODUCTION: Research opportunities associated with the proliferation of the electronic health record (EHR), big data initiatives, and innovative approaches to trial design can present challenges for obtaining and documenting informed consent. ...We e …
INTRODUCTION: Research opportunities associated with the proliferation of the electronic health record (EHR), big da
Anorexia nervosa through the lens of a severe and enduring experience: 'lost in a big world'.
Kiely L, Conti J, Hay P. Kiely L, et al. J Eat Disord. 2024 Jan 22;12(1):12. doi: 10.1186/s40337-023-00953-2. J Eat Disord. 2024. PMID: 38254163 Free PMC article.
These factors are implicated in illness persistence eliciting opportunities for further research testing including diagnostic considerations and treatment directions. ...One such way to build understanding of a condition is via the stories of those who experience
These factors are implicated in illness persistence eliciting opportunities for further research testing including diagnostic …
"What Goes Around Comes Around": Lessons Learned from Economic Evaluations of Personalized Medicine Applied to Digital Medicine.
Phillips KA, Douglas MP, Trosman JR, Marshall DA. Phillips KA, et al. Value Health. 2017 Jan;20(1):47-53. doi: 10.1016/j.jval.2016.08.736. Value Health. 2017. PMID: 28212968 Free PMC article.
BACKGROUND: The growth of "big data" and the emphasis on patient-centered health care have led to the increasing use of two key technologies: personalized medicine and digital medicine. ...CONCLUSIONS: We conclude that more evidence on the effectiveness of digital m …
BACKGROUND: The growth of "big data" and the emphasis on patient-centered health care have led to the increasing use of two ke …
Transdisciplinary synthesis for ecosystem science, policy and management: The Australian experience.
Lynch AJ, Thackway R, Specht A, Beggs PJ, Brisbane S, Burns EL, Byrne M, Capon SJ, Casanova MT, Clarke PA, Davies JM, Dovers S, Dwyer RG, Ens E, Fisher DO, Flanigan M, Garnier E, Guru SM, Kilminster K, Locke J, Mac Nally R, McMahon KM, Mitchell PJ, Pierson JC, Rodgers EM, Russell-Smith J, Udy J, Waycott M. Lynch AJ, et al. Sci Total Environ. 2015 Nov 15;534:173-84. doi: 10.1016/j.scitotenv.2015.04.100. Epub 2015 May 6. Sci Total Environ. 2015. PMID: 25957785
These centres are finding an expanding role due to ever-accumulating data and the need for more and better opportunities to develop transdisciplinary and holistic approaches to solve real-world problems. ...Scientists and managers were brought together to actively c …
These centres are finding an expanding role due to ever-accumulating data and the need for more and better opportunities to de …
11 results