Some like it hot: testosterone predicts laboratory eating behavior of spicy food.
Physiol Behav. 2015.
PMID: 25462592
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some like it not: testosterone predict laboratory eating behaviors of spice food
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Some like it hot: Testosterone predicts laboratory eating behavior of spicy food instead
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Lead- and drug-like compounds: the rule-of-five revolution.
Drug Discov Today Technol. 2004 Dec;1(4):337-41. doi: 10.1016/j.ddtec.2004.11.007.
Drug Discov Today Technol. 2004.
PMID: 24981612
Trends in the RO5 literature explosion that can be discerned are the further definitions of drug-like. This topic is explored in terms of drug-like physicochemical features, drug-like structural features, a comparison of drug-like and non-drug-like …
Trends in the RO5 literature explosion that can be discerned are the further definitions of drug-like. This topic is explored in term …
Toll-like receptor signaling.
Cold Spring Harb Perspect Biol. 2013 Jan 1;5(1):a011247. doi: 10.1101/cshperspect.a011247.
Cold Spring Harb Perspect Biol. 2013.
PMID: 23284045
Free PMC article.
Review.
Toll-like receptors sense pathogen-associated molecular patterns (e.g., lipopolysaccharides) and trigger gene-expression changes that ultimately eradicate the invading microbes....
Toll-like receptors sense pathogen-associated molecular patterns (e.g., lipopolysaccharides) and trigger gene-expression changes that …
Prion-Like Domains in Phagobiota.
Front Microbiol. 2017 Nov 15;8:2239. doi: 10.3389/fmicb.2017.02239. eCollection 2017.
Front Microbiol. 2017.
PMID: 29187840
Free PMC article.
Here, we examined whether bacteriophages contain prion-like proteins and whether these prion-like protein domains are involved in the regulation of homeostasis. We used a computational algorithm, prion-like amino acid composition, to detect prion-like …
Here, we examined whether bacteriophages contain prion-like proteins and whether these prion-like protein domains are involved …
Single-cell RNA sequencing reveals the vascular smooth muscle cell phenotypic landscape in aortic aneurysm.
Cell Commun Signal. 2023 May 15;21(1):113. doi: 10.1186/s12964-023-01120-5.
Cell Commun Signal. 2023.
PMID: 37189183
Free PMC article.
RESULTS: A total of 7150 VSMCs were categorize into 6 phenotypes: contractile VSMCs, fibroblast-like VSMCs, T-cell-like VSMCs, adipocyte-like VSMCs, macrophage-like VSMCs, and mesenchymal-like VSMCs. The proportions of T-cell-like VSMCs, …
RESULTS: A total of 7150 VSMCs were categorize into 6 phenotypes: contractile VSMCs, fibroblast-like VSMCs, T-cell-like VSMCs, …
Toll-like receptors.
J Biol Regul Homeost Agents. 2008 Jan-Mar;22(1):17-26.
J Biol Regul Homeost Agents. 2008.
PMID: 18394314
Review.
Toll-like receptors are a family of transmembrane receptors responsible for recognition and initiation of a response to invading microbes by the immune system. ...Some of ten toll-like receptors identified in humans are able to recognise several pathogen-associated …
Toll-like receptors are a family of transmembrane receptors responsible for recognition and initiation of a response to invading micr …
Toll-like receptors in neonatal sepsis.
Acta Paediatr. 2013 Jun;102(6):572-8. doi: 10.1111/apa.12201.
Acta Paediatr. 2013.
PMID: 23419040
Review.
Toll-like receptors are vital transmembrane receptors that initiate the innate immune response to many micro-organisms. ...CONCLUSION: Toll-like receptor modulation may potentially be used as immunomodulators in the management of neonatal sepsis....
Toll-like receptors are vital transmembrane receptors that initiate the innate immune response to many micro-organisms. ...CONCLUSION …
Toll-like receptor and RIG-I-like receptor signaling.
Ann N Y Acad Sci. 2008 Nov;1143:1-20. doi: 10.1196/annals.1443.020.
Ann N Y Acad Sci. 2008.
PMID: 19076341
Review.
Toll-like receptors (TLRs) and RIG-I-like receptors (RLRs) constitute distinct families of pattern-recognition receptors that sense nucleic acids derived from viruses and trigger antiviral innate immune responses. ...
Toll-like receptors (TLRs) and RIG-I-like receptors (RLRs) constitute distinct families of pattern-recognition receptors that …
Genetics: ANGPTL3 deficiency protects from CAD.
Nat Rev Cardiol. 2017 Jun;14(6):316. doi: 10.1038/nrcardio.2017.67. Epub 2017 May 4.
Nat Rev Cardiol. 2017.
PMID: 28470173
Review.
No abstract available.
Have any strategies in Ph-like ALL been shown to be effective?
Best Pract Res Clin Haematol. 2021 Mar;34(1):101242. doi: 10.1016/j.beha.2021.101242. Epub 2021 Jan 11.
Best Pract Res Clin Haematol. 2021.
PMID: 33762097
Review.
Philadelphia-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk subset of B-cell ALL characterized by high rates of treatment failure. ...Notably, Ph-like ALL is not an uncommon entity in adults, and it's prevalence extends to older patients wit …
Philadelphia-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk subset of B-cell ALL characterized by high rates …
TLR ignores methylated RNA?
Immunity. 2005 Aug;23(2):111-3. doi: 10.1016/j.immuni.2005.08.003.
Immunity. 2005.
PMID: 16111629
Free article.
Review.
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