Sommer ME - Search Results

1

Crystal structure of pre-activated arrestin p44.

Kim YJ, Hofmann KP, Ernst OP, Scheerer P, Choe HW, Sommer ME. Kim YJ, et al. Among authors: sommer me. Nature. 2013 May 2;497(7447):142-6. doi: 10.1038/nature12133. Epub 2013 Apr 21. Nature. 2013. PMID: 23604253

2

Molecular mechanism of GPCR-mediated arrestin activation.

Latorraca NR, Wang JK, Bauer B, Townshend RJL, Hollingsworth SA, Olivieri JE, Xu HE, Sommer ME, Dror RO. Latorraca NR, et al. Among authors: sommer me. Nature. 2018 May;557(7705):452-456. doi: 10.1038/s41586-018-0077-3. Epub 2018 May 2. Nature. 2018. PMID: 29720655 Free PMC article.

3

C-edge loops of arrestin function as a membrane anchor.

Lally CC, Bauer B, Selent J, Sommer ME. Lally CC, et al. Among authors: sommer me. Nat Commun. 2017 Feb 21;8:14258. doi: 10.1038/ncomms14258. Nat Commun. 2017. PMID: 28220785 Free PMC article.

4

Formation and decay of the arrestin·rhodopsin complex in native disc membranes.

Beyrière F, Sommer ME, Szczepek M, Bartl FJ, Hofmann KP, Heck M, Ritter E. Beyrière F, et al. Among authors: sommer me. J Biol Chem. 2015 May 15;290(20):12919-28. doi: 10.1074/jbc.M114.620898. Epub 2015 Apr 6. J Biol Chem. 2015. PMID: 25847250 Free PMC article.

5

Crystal structure of a common GPCR-binding interface for G protein and arrestin.

Szczepek M, Beyrière F, Hofmann KP, Elgeti M, Kazmin R, Rose A, Bartl FJ, von Stetten D, Heck M, Sommer ME, Hildebrand PW, Scheerer P. Szczepek M, et al. Among authors: sommer me. Nat Commun. 2014 Sep 10;5:4801. doi: 10.1038/ncomms5801. Nat Commun. 2014. PMID: 25205354 Free PMC article.

6

Not just signal shutoff: the protective role of arrestin-1 in rod cells.

Sommer ME, Hofmann KP, Heck M. Sommer ME, et al. Handb Exp Pharmacol. 2014;219:101-16. doi: 10.1007/978-3-642-41199-1_5. Handb Exp Pharmacol. 2014. PMID: 24292826

7

Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation.

Mayer D, Damberger FF, Samarasimhareddy M, Feldmueller M, Vuckovic Z, Flock T, Bauer B, Mutt E, Zosel F, Allain FHT, Standfuss J, Schertler GFX, Deupi X, Sommer ME, Hurevich M, Friedler A, Veprintsev DB. Mayer D, et al. Among authors: sommer me. Nat Commun. 2019 Mar 19;10(1):1261. doi: 10.1038/s41467-019-09204-y. Nat Commun. 2019. PMID: 30890705 Free PMC article.

8

Structural mechanism of arrestin activation.

Scheerer P, Sommer ME. Scheerer P, et al. Among authors: sommer me. Curr Opin Struct Biol. 2017 Aug;45:160-169. doi: 10.1016/j.sbi.2017.05.001. Epub 2017 Jun 7. Curr Opin Struct Biol. 2017. PMID: 28600951 Free article. Review.

9

Functional map of arrestin binding to phosphorylated opsin, with and without agonist.

Peterhans C, Lally CC, Ostermaier MK, Sommer ME, Standfuss J. Peterhans C, et al. Among authors: sommer me. Sci Rep. 2016 Jun 28;6:28686. doi: 10.1038/srep28686. Sci Rep. 2016. PMID: 27350090 Free PMC article.

10

Structure-based biophysical analysis of the interaction of rhodopsin with G protein and arrestin.

Sommer ME, Elgeti M, Hildebrand PW, Szczepek M, Hofmann KP, Scheerer P. Sommer ME, et al. Methods Enzymol. 2015;556:563-608. doi: 10.1016/bs.mie.2014.12.014. Epub 2015 Mar 6. Methods Enzymol. 2015. PMID: 25857800

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