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Opioid activation of toll-like receptor 4 contributes to drug reinforcement.
Hutchinson MR, Northcutt AL, Hiranita T, Wang X, Lewis SS, Thomas J, van Steeg K, Kopajtic TA, Loram LC, Sfregola C, Galer E, Miles NE, Bland ST, Amat J, Rozeske RR, Maslanik T, Chapman TR, Strand KA, Fleshner M, Bachtell RK, Somogyi AA, Yin H, Katz JL, Rice KC, Maier SF, Watkins LR. Hutchinson MR, et al. Among authors: somogyi aa. J Neurosci. 2012 Aug 15;32(33):11187-200. doi: 10.1523/JNEUROSCI.0684-12.2012. J Neurosci. 2012. PMID: 22895704 Free PMC article.
Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia.
Hutchinson MR, Coats BD, Lewis SS, Zhang Y, Sprunger DB, Rezvani N, Baker EM, Jekich BM, Wieseler JL, Somogyi AA, Martin D, Poole S, Judd CM, Maier SF, Watkins LR. Hutchinson MR, et al. Among authors: somogyi aa. Brain Behav Immun. 2008 Nov;22(8):1178-89. doi: 10.1016/j.bbi.2008.05.004. Epub 2008 Jul 2. Brain Behav Immun. 2008. PMID: 18599265 Free PMC article.
Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences.
Hutchinson MR, Lewis SS, Coats BD, Rezvani N, Zhang Y, Wieseler JL, Somogyi AA, Yin H, Maier SF, Rice KC, Watkins LR. Hutchinson MR, et al. Among authors: somogyi aa. Neuroscience. 2010 May 19;167(3):880-93. doi: 10.1016/j.neuroscience.2010.02.011. Epub 2010 Feb 21. Neuroscience. 2010. PMID: 20178837 Free PMC article.
300 results