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The cystic fibrosis transmembrane conductance regulator. Effects of the most common cystic fibrosis-causing mutation on the secondary structure and stability of a synthetic peptide.
Thomas PJ, Shenbagamurthi P, Sondek J, Hullihen JM, Pedersen PL. Thomas PJ, et al. Among authors: sondek j. J Biol Chem. 1992 Mar 25;267(9):5727-30. J Biol Chem. 1992. PMID: 1372891
J., Shenbagamurthi, P., Ysern, X., and Pedersen, P. L. (1991) Science 251, 555-557). A peptide lacking this critical residue, but otherwise corresponding to this crucial part of the protein, now also has been chemically synthesized and purified. ...
J., Shenbagamurthi, P., Ysern, X., and Pedersen, P. L. (1991) Science 251, 555-557). A peptide lacking this critical residue, but oth
Functional analysis of cdc42 residues required for Guanine nucleotide exchange.
Rossman KL, Worthylake DK, Snyder JT, Cheng L, Whitehead IP, Sondek J. Rossman KL, et al. Among authors: sondek j. J Biol Chem. 2002 Dec 27;277(52):50893-8. doi: 10.1074/jbc.M208580200. Epub 2002 Oct 24. J Biol Chem. 2002. PMID: 12401782
SmgGDS is a guanine nucleotide exchange factor that specifically activates RhoA and RhoC.
Hamel B, Monaghan-Benson E, Rojas RJ, Temple BR, Marston DJ, Burridge K, Sondek J. Hamel B, et al. Among authors: sondek j. J Biol Chem. 2011 Apr 8;286(14):12141-8. doi: 10.1074/jbc.M110.191122. Epub 2011 Jan 17. J Biol Chem. 2011. PMID: 21242305 Free PMC article.
Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting.
Baumeister MA, Martinu L, Rossman KL, Sondek J, Lemmon MA, Chou MM. Baumeister MA, et al. Among authors: sondek j. J Biol Chem. 2003 Mar 28;278(13):11457-64. doi: 10.1074/jbc.M211901200. Epub 2003 Jan 13. J Biol Chem. 2003. PMID: 12525493
Requirement for C-terminal sequences in regulation of Ect2 guanine nucleotide exchange specificity and transformation.
Solski PA, Wilder RS, Rossman KL, Sondek J, Cox AD, Campbell SL, Der CJ. Solski PA, et al. Among authors: sondek j. J Biol Chem. 2004 Jun 11;279(24):25226-33. doi: 10.1074/jbc.M313792200. Epub 2004 Apr 8. J Biol Chem. 2004. PMID: 15073184
Mechanism of phosphorylation-induced activation of phospholipase C-gamma isozymes.
Gresset A, Hicks SN, Harden TK, Sondek J. Gresset A, et al. Among authors: sondek j. J Biol Chem. 2010 Nov 12;285(46):35836-47. doi: 10.1074/jbc.M110.166512. Epub 2010 Aug 31. J Biol Chem. 2010. PMID: 20807769 Free PMC article.
Structural and biochemical characterization of CIB1 delineates a new family of EF-hand-containing proteins.
Gentry HR, Singer AU, Betts L, Yang C, Ferrara JD, Sondek J, Parise LV. Gentry HR, et al. Among authors: sondek j. J Biol Chem. 2005 Mar 4;280(9):8407-15. doi: 10.1074/jbc.M411515200. Epub 2004 Dec 1. J Biol Chem. 2005. PMID: 15574431
Direct activation of phospholipase C-epsilon by Rho.
Wing MR, Snyder JT, Sondek J, Harden TK. Wing MR, et al. Among authors: sondek j. J Biol Chem. 2003 Oct 17;278(42):41253-8. doi: 10.1074/jbc.M306904200. Epub 2003 Aug 4. J Biol Chem. 2003. PMID: 12900402
Molecular basis of CIB binding to the integrin alpha IIb cytoplasmic domain.
Barry WT, Boudignon-Proudhon C, Shock DD, McFadden A, Weiss JM, Sondek J, Parise LV. Barry WT, et al. Among authors: sondek j. J Biol Chem. 2002 Aug 9;277(32):28877-83. doi: 10.1074/jbc.M202983200. Epub 2002 May 21. J Biol Chem. 2002. PMID: 12023286
Membrane-induced allosteric control of phospholipase C-β isozymes.
Charpentier TH, Waldo GL, Barrett MO, Huang W, Zhang Q, Harden TK, Sondek J. Charpentier TH, et al. Among authors: sondek j. J Biol Chem. 2014 Oct 24;289(43):29545-57. doi: 10.1074/jbc.M114.586784. Epub 2014 Sep 5. J Biol Chem. 2014. PMID: 25193662 Free PMC article.
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