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A fraction of the mRNA 5' cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus.
Lejbkowicz F, Goyer C, Darveau A, Neron S, Lemieux R, Sonenberg N. Lejbkowicz F, et al. Proc Natl Acad Sci U S A. 1992 Oct 15;89(20):9612-6. doi: 10.1073/pnas.89.20.9612. Proc Natl Acad Sci U S A. 1992. PMID: 1384058 Free PMC article.
The 5' cap structure m7GpppN (where N is any nucleotide) is a ubiquitous feature of cellular eukaryotic mRNAs. The cap is multifunctional as it is involved in translation, nucleocytoplasmic transport, splicing, and stabilization of mRNA against 5' exonucleolytic degradatio …
The 5' cap structure m7GpppN (where N is any nucleotide) is a ubiquitous feature of cellular eukaryotic mRNAs. The cap is multifuncti …
mRNAs containing extensive secondary structure in their 5' non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E.
Koromilas AE, Lazaris-Karatzas A, Sonenberg N. Koromilas AE, et al. EMBO J. 1992 Nov;11(11):4153-8. EMBO J. 1992. PMID: 1396596 Free PMC article.
Cellular eukaryotic mRNAs (except organellar) contain at the 5' terminus the structure m7(5')Gppp(5')N (where N is any nucleotide), termed cap. ...
Cellular eukaryotic mRNAs (except organellar) contain at the 5' terminus the structure m7(5')Gppp(5')N (where N is any nucleot …
ATP hydrolysis by initiation factor 4A is required for translation initiation in Saccharomyces cerevisiae.
Blum S, Schmid SR, Pause A, Buser P, Linder P, Sonenberg N, Trachsel H. Blum S, et al. Proc Natl Acad Sci U S A. 1992 Aug 15;89(16):7664-8. doi: 10.1073/pnas.89.16.7664. Proc Natl Acad Sci U S A. 1992. PMID: 1502180 Free PMC article.
Ras mediates translation initiation factor 4E-induced malignant transformation.
Lazaris-Karatzas A, Smith MR, Frederickson RM, Jaramillo ML, Liu YL, Kung HF, Sonenberg N. Lazaris-Karatzas A, et al. Genes Dev. 1992 Sep;6(9):1631-42. doi: 10.1101/gad.6.9.1631. Genes Dev. 1992. PMID: 1516827
Translation initiation factor eIF-4E binds to the eukaryotic mRNA 5' cap structure (m7 GpppN, where N is any nucleotide). eIF-4E is a limiting factor in translation and plays a key role in regulation of translation. ...
Translation initiation factor eIF-4E binds to the eukaryotic mRNA 5' cap structure (m7 GpppN, where N is any nucleotide). eIF-4E is a …
Phosphorylation of translation initiation factor eIF-4E is induced in a ras-dependent manner during nerve growth factor-mediated PC12 cell differentiation.
Frederickson RM, Mushynski WE, Sonenberg N. Frederickson RM, et al. Mol Cell Biol. 1992 Mar;12(3):1239-47. doi: 10.1128/mcb.12.3.1239. Mol Cell Biol. 1992. PMID: 1545805 Free PMC article.
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