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Structural details of the OxyR peroxide-sensing mechanism.
Jo I, Chung IY, Bae HW, Kim JS, Song S, Cho YH, Ha NC. Jo I, et al. Among authors: Song S. Proc Natl Acad Sci U S A. 2015 May 19;112(20):6443-8. doi: 10.1073/pnas.1424495112. Epub 2015 Apr 30. Proc Natl Acad Sci U S A. 2015. PMID: 25931525 Free PMC article.
Structural basis for the sequestration of the anti-σ(70) factor Rsd from σ(70) by the histidine-containing phosphocarrier protein HPr.
Park YH, Um SH, Song S, Seok YJ, Ha NC. Park YH, et al. Among authors: Song S. Acta Crystallogr D Biol Crystallogr. 2015 Oct;71(Pt 10):1998-2008. doi: 10.1107/S1399004715013759. Epub 2015 Sep 26. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 26457424
This anti-sigma factor sequesters the housekeeping sigma factor σ(70) to facilitate switching of the sigma subunit on RNA polymerase from σ(70) to the stress-responsive sigma factor σ(S) in stationary-phase cells. ...
This anti-sigma factor sequesters the housekeeping sigma factor σ(70) to facilitate switching of the sigma subunit on RNA polymerase from σ( …
Stoichiometry and mechanistic implications of the MacAB-TolC tripartite efflux pump.
Jo I, Hong S, Lee M, Song S, Kim JS, Mitra AK, Hyun J, Lee K, Ha NC. Jo I, et al. Among authors: Song S. Biochem Biophys Res Commun. 2017 Dec 16;494(3-4):668-673. doi: 10.1016/j.bbrc.2017.10.102. Epub 2017 Oct 20. Biochem Biophys Res Commun. 2017. PMID: 29061301
Crystal structure of Streptomyces coelicolor RraAS2, an unusual member of the RNase E inhibitor RraA protein family.
Park N, Heo J, Song S, Jo I, Lee K, Ha NC. Park N, et al. Among authors: Song S. J Microbiol. 2017 May;55(5):388-395. doi: 10.1007/s12275-017-7053-8. Epub 2017 Apr 29. J Microbiol. 2017. PMID: 28455590
RraAS1 and RraAS2 inhibit RNase ES ribonuclease activity in S. coelicolor. RraAS1 and RraAS2 have a C-terminal extension region unlike typical bacterial RraA proteins. ...Our findings present the first bacterial RraA that has a hexameric assembly with a C-terminal extension α-helical region, which plays an essential role in the regulation of RNase ES activity in S. coelicolor....
RraAS1 and RraAS2 inhibit RNase ES ribonuclease activity in S. coelicolor. RraAS1 and RraAS2 have a C-terminal extension region unlik …
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