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Page 1
Evoking picomolar binding in RNA by a single phosphorodithioate linkage.
Abeydeera ND, Egli M, Cox N, Mercier K, Conde JN, Pallan PS, Mizurini DM, Sierant M, Hibti FE, Hassell T, Wang T, Liu FW, Liu HM, Martinez C, Sood AK, Lybrand TP, Frydman C, Monteiro RQ, Gomer RH, Nawrot B, Yang X. Abeydeera ND, et al. Among authors: sood ak. Nucleic Acids Res. 2016 Sep 30;44(17):8052-64. doi: 10.1093/nar/gkw725. Epub 2016 Aug 26. Nucleic Acids Res. 2016. PMID: 27566147 Free PMC article.
2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity.
Wu SY, Yang X, Gharpure KM, Hatakeyama H, Egli M, McGuire MH, Nagaraja AS, Miyake TM, Rupaimoole R, Pecot CV, Taylor M, Pradeep S, Sierant M, Rodriguez-Aguayo C, Choi HJ, Previs RA, Armaiz-Pena GN, Huang L, Martinez C, Hassell T, Ivan C, Sehgal V, Singhania R, Han HD, Su C, Kim JH, Dalton HJ, Kovvali C, Keyomarsi K, McMillan NA, Overwijk WW, Liu J, Lee JS, Baggerly KA, Lopez-Berestein G, Ram PT, Nawrot B, Sood AK. Wu SY, et al. Among authors: sood ak. Nat Commun. 2014 Mar 12;5:3459. doi: 10.1038/ncomms4459. Nat Commun. 2014. PMID: 24619206 Free PMC article.
Biological roles of the Delta family Notch ligand Dll4 in tumor and endothelial cells in ovarian cancer.
Hu W, Lu C, Dong HH, Huang J, Shen DY, Stone RL, Nick AM, Shahzad MM, Mora E, Jennings NB, Lee SJ, Roh JW, Matsuo K, Nishimura M, Goodman BW, Jaffe RB, Langley RR, Deavers MT, Lopez-Berestein G, Coleman RL, Sood AK. Hu W, et al. Among authors: sood ak. Cancer Res. 2011 Sep 15;71(18):6030-9. doi: 10.1158/0008-5472.CAN-10-2719. Epub 2011 Jul 27. Cancer Res. 2011. PMID: 21795478 Free PMC article.
Biological significance of HORMA domain containing protein 1 (HORMAD1) in epithelial ovarian carcinoma.
Shahzad MM, Shin YH, Matsuo K, Lu C, Nishimura M, Shen DY, Kang Y, Hu W, Mora EM, Rodriguez-Aguayo C, Kapur A, Bottsford-Miller J, Lopez-Berestein G, Rajkovic A, Sood AK. Shahzad MM, et al. Among authors: sood ak. Cancer Lett. 2013 Apr 28;330(2):123-9. doi: 10.1016/j.canlet.2012.07.001. Epub 2012 Jul 7. Cancer Lett. 2013. PMID: 22776561 Free PMC article. Review.
Therapeutic Silencing of Bcl-2 by Systemically Administered siRNA Nanotherapeutics Inhibits Tumor Growth by Autophagy and Apoptosis and Enhances the Efficacy of Chemotherapy in Orthotopic Xenograft Models of ER (-) and ER (+) Breast Cancer.
Tekedereli I, Alpay SN, Akar U, Yuca E, Ayugo-Rodriguez C, Han HD, Sood AK, Lopez-Berestein G, Ozpolat B. Tekedereli I, et al. Among authors: sood ak. Mol Ther Nucleic Acids. 2013 Sep 10;2(9):e121. doi: 10.1038/mtna.2013.45. Mol Ther Nucleic Acids. 2013. PMID: 24022053 Free PMC article.
Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy.
Mangala LS, Wang H, Jiang D, Wu SY, Somasunderam A, Volk DE, Lokesh GLR, Li X, Pradeep S, Yang X, Haemmerle M, Rodriguez-Aguayo C, Nagaraja AS, Rupaimoole R, Bayraktar E, Bayraktar R, Li L, Tanaka T, Hu W, Ivan C, Gharpure KM, McGuire MH, Thiviyanathan V, Zhang X, Maiti SN, Bulayeva N, Choi HJ, Dorniak PL, Cooper LJ, Rosenblatt KP, Lopez-Berestein G, Gorenstein DG, Sood AK. Mangala LS, et al. Among authors: sood ak. JCI Insight. 2016 Oct 20;1(17):e87754. doi: 10.1172/jci.insight.87754. JCI Insight. 2016. PMID: 27777972 Free PMC article.
Therapeutic Targeting of AXL Receptor Tyrosine Kinase Inhibits Tumor Growth and Intraperitoneal Metastasis in Ovarian Cancer Models.
Kanlikilicer P, Ozpolat B, Aslan B, Bayraktar R, Gurbuz N, Rodriguez-Aguayo C, Bayraktar E, Denizli M, Gonzalez-Villasana V, Ivan C, Lokesh GLR, Amero P, Catuogno S, Haemmerle M, Wu SY, Mitra R, Gorenstein DG, Volk DE, de Franciscis V, Sood AK, Lopez-Berestein G. Kanlikilicer P, et al. Among authors: sood ak. Mol Ther Nucleic Acids. 2017 Dec 15;9:251-262. doi: 10.1016/j.omtn.2017.06.023. Epub 2017 Jul 5. Mol Ther Nucleic Acids. 2017. PMID: 29246304 Free PMC article.
PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis.
Rodriguez-Aguayo C, Bayraktar E, Ivan C, Aslan B, Mai J, He G, Mangala LS, Jiang D, Nagaraja AS, Ozpolat B, Chavez-Reyes A, Ferrari M, Mitra R, Siddik ZH, Shen H, Yang X, Sood AK, Lopez-Berestein G. Rodriguez-Aguayo C, et al. Among authors: sood ak. EBioMedicine. 2019 Feb;40:290-304. doi: 10.1016/j.ebiom.2018.11.045. Epub 2019 Jan 14. EBioMedicine. 2019. PMID: 30655206 Free PMC article.
Circular RNAs in Cancer.
Bach DH, Lee SK, Sood AK. Bach DH, et al. Among authors: sood ak. Mol Ther Nucleic Acids. 2019 Jun 7;16:118-129. doi: 10.1016/j.omtn.2019.02.005. Epub 2019 Feb 16. Mol Ther Nucleic Acids. 2019. PMID: 30861414 Free PMC article. Review.
1,135 results