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The glucocorticoid receptor is overexpressed in malignant adrenocortical tumors.
Tacon LJ, Soon PS, Gill AJ, Chou AS, Clarkson A, Botling J, Stalberg PL, Skogseid BM, Robinson BG, Sidhu SB, Clifton-Bligh RJ. Tacon LJ, et al. Among authors: soon ps. J Clin Endocrinol Metab. 2009 Nov;94(11):4591-9. doi: 10.1210/jc.2009-0546. Epub 2009 Oct 9. J Clin Endocrinol Metab. 2009. PMID: 19820023
Comprehensive re-sequencing of adrenal aldosterone producing lesions reveal three somatic mutations near the KCNJ5 potassium channel selectivity filter.
Åkerström T, Crona J, Delgado Verdugo A, Starker LF, Cupisti K, Willenberg HS, Knoefel WT, Saeger W, Feller A, Ip J, Soon P, Anlauf M, Alesina PF, Schmid KW, Decaussin M, Levillain P, Wängberg B, Peix JL, Robinson B, Zedenius J, Bäckdahl M, Caramuta S, Iwen KA, Botling J, Stålberg P, Kraimps JL, Dralle H, Hellman P, Sidhu S, Westin G, Lehnert H, Walz MK, Åkerström G, Carling T, Choi M, Lifton RP, Björklund P. Åkerström T, et al. PLoS One. 2012;7(7):e41926. doi: 10.1371/journal.pone.0041926. Epub 2012 Jul 27. PLoS One. 2012. PMID: 22848660 Free PMC article.
43 results