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Gestational exposure of mice to secondhand cigarette smoke causes bronchopulmonary dysplasia blocked by the nicotinic receptor antagonist mecamylamine.
Singh SP, Gundavarapu S, Smith KR, Chand HS, Saeed AI, Mishra NC, Hutt J, Barrett EG, Husain M, Harrod KS, Langley RJ, Sopori ML. Singh SP, et al. Among authors: sopori ml. Environ Health Perspect. 2013 Aug;121(8):957-64. doi: 10.1289/ehp.1306611. Epub 2013 Jun 11. Environ Health Perspect. 2013. PMID: 23757602 Free PMC article.
Role of nicotinic receptors and acetylcholine in mucous cell metaplasia, hyperplasia, and airway mucus formation in vitro and in vivo.
Gundavarapu S, Wilder JA, Mishra NC, Rir-Sima-Ah J, Langley RJ, Singh SP, Saeed AI, Jaramillo RJ, Gott KM, Peña-Philippides JC, Harrod KS, McIntosh JM, Buch S, Sopori ML. Gundavarapu S, et al. Among authors: sopori ml. J Allergy Clin Immunol. 2012 Sep;130(3):770-780.e11. doi: 10.1016/j.jaci.2012.04.002. Epub 2012 May 9. J Allergy Clin Immunol. 2012. PMID: 22578901 Free PMC article.
Maternal exposure to secondhand cigarette smoke primes the lung for induction of phosphodiesterase-4D5 isozyme and exacerbated Th2 responses: rolipram attenuates the airway hyperreactivity and muscarinic receptor expression but not lung inflammation and atopy.
Singh SP, Mishra NC, Rir-Sima-Ah J, Campen M, Kurup V, Razani-Boroujerdi S, Sopori ML. Singh SP, et al. Among authors: sopori ml. J Immunol. 2009 Aug 1;183(3):2115-21. doi: 10.4049/jimmunol.0900826. Epub 2009 Jul 13. J Immunol. 2009. PMID: 19596983 Free PMC article.
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