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Human serum Paraoxonase/Arylesterase's retained hydrophobic N-terminal leader sequence associates with HDLs by binding phospholipids : apolipoprotein A-I stabilizes activity.
Sorenson RC, Bisgaier CL, Aviram M, Hsu C, Billecke S, La Du BN. Sorenson RC, et al. Arterioscler Thromb Vasc Biol. 1999 Sep;19(9):2214-25. doi: 10.1161/01.atv.19.9.2214. Arterioscler Thromb Vasc Biol. 1999. PMID: 10479665
Properties of the retained N-terminal hydrophobic leader sequence in human serum paraoxonase/arylesterase.
Sorenson RC, Aviram M, Bisgaier CL, Billecke S, Hsu C, La Du BN. Sorenson RC, et al. Chem Biol Interact. 1999 May 14;119-120:243-9. doi: 10.1016/s0009-2797(99)00033-2. Chem Biol Interact. 1999. PMID: 10421458
Evidence that several conserved histidine residues are required for hydrolytic activity of human paraoxonase/arylesterase.
Doorn JA, Sorenson RC, Billecke SS, Hsu C, La Du BN. Doorn JA, et al. Among authors: sorenson rc. Chem Biol Interact. 1999 May 14;119-120:235-41. doi: 10.1016/s0009-2797(99)00032-0. Chem Biol Interact. 1999. PMID: 10421457
The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family.
Primo-Parmo SL, Sorenson RC, Teiber J, La Du BN. Primo-Parmo SL, et al. Among authors: sorenson rc. Genomics. 1996 May 1;33(3):498-507. doi: 10.1006/geno.1996.0225. Genomics. 1996. PMID: 8661009
Reconsideration of the catalytic center and mechanism of mammalian paraoxonase/arylesterase.
Sorenson RC, Primo-Parmo SL, Kuo CL, Adkins S, Lockridge O, La Du BN. Sorenson RC, et al. Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7187-91. doi: 10.1073/pnas.92.16.7187. Proc Natl Acad Sci U S A. 1995. PMID: 7638166 Free PMC article.
The genetic mapping and gene structure of mouse paraoxonase/arylesterase.
Sorenson RC, Primo-Parmo SL, Camper SA, La Du BN. Sorenson RC, et al. Genomics. 1995 Dec 10;30(3):431-8. doi: 10.1006/geno.1995.1261. Genomics. 1995. PMID: 8825627
On the physiological role(s) of the paraoxonases.
La Du BN, Aviram M, Billecke S, Navab M, Primo-Parmo S, Sorenson RC, Standiford TJ. La Du BN, et al. Among authors: sorenson rc. Chem Biol Interact. 1999 May 14;119-120:379-88. doi: 10.1016/s0009-2797(99)00049-6. Chem Biol Interact. 1999. PMID: 10421474 Review.
Paraoxonase active site required for protection against LDL oxidation involves its free sulfhydryl group and is different from that required for its arylesterase/paraoxonase activities: selective action of human paraoxonase allozymes Q and R.
Aviram M, Billecke S, Sorenson R, Bisgaier C, Newton R, Rosenblat M, Erogul J, Hsu C, Dunlop C, La Du B. Aviram M, et al. Arterioscler Thromb Vasc Biol. 1998 Oct;18(10):1617-24. doi: 10.1161/01.atv.18.10.1617. Arterioscler Thromb Vasc Biol. 1998. PMID: 9763535
Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants.
Aviram M, Rosenblat M, Billecke S, Erogul J, Sorenson R, Bisgaier CL, Newton RS, La Du B. Aviram M, et al. Free Radic Biol Med. 1999 Apr;26(7-8):892-904. doi: 10.1016/s0891-5849(98)00272-x. Free Radic Biol Med. 1999. PMID: 10232833
High density associated enzymes: their role in vascular biology.
Navab M, Hama SY, Hough GP, Hedrick CC, Sorenson R, La Du BN, Kobashigawa JA, Fonarow GC, Berliner JA, Laks H, Fogelman AM. Navab M, et al. Curr Opin Lipidol. 1998 Oct;9(5):449-56. doi: 10.1097/00041433-199810000-00009. Curr Opin Lipidol. 1998. PMID: 9812199 Review.
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