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Paraoxonase active site required for protection against LDL oxidation involves its free sulfhydryl group and is different from that required for its arylesterase/paraoxonase activities: selective action of human paraoxonase allozymes Q and R.
Aviram M, Billecke S, Sorenson R, Bisgaier C, Newton R, Rosenblat M, Erogul J, Hsu C, Dunlop C, La Du B. Aviram M, et al. Arterioscler Thromb Vasc Biol. 1998 Oct;18(10):1617-24. doi: 10.1161/01.atv.18.10.1617. Arterioscler Thromb Vasc Biol. 1998. PMID: 9763535
On the physiological role(s) of the paraoxonases.
La Du BN, Aviram M, Billecke S, Navab M, Primo-Parmo S, Sorenson RC, Standiford TJ. La Du BN, et al. Among authors: sorenson rc. Chem Biol Interact. 1999 May 14;119-120:379-88. doi: 10.1016/s0009-2797(99)00049-6. Chem Biol Interact. 1999. PMID: 10421474 Review.
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