Sormunen R - Search Results

1

Lack of P4H-TM in mice results in age-related retinal and renal alterations.

Leinonen H, Rossi M, Salo AM, Tiainen P, Hyvärinen J, Pitkänen M, Sormunen R, Miinalainen I, Zhang C, Soininen R, Kivirikko KI, Koskelainen A, Tanila H, Myllyharju J, Koivunen P. Leinonen H, et al. Among authors: sormunen r. Hum Mol Genet. 2016 Sep 1;25(17):3810-3823. doi: 10.1093/hmg/ddw228. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466183

2

HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury.

Karsikas S, Myllymäki M, Heikkilä M, Sormunen R, Kivirikko KI, Myllyharju J, Serpi R, Koivunen P. Karsikas S, et al. Among authors: sormunen r. J Mol Med (Berl). 2016 Mar;94(3):301-10. doi: 10.1007/s00109-015-1349-0. Epub 2015 Oct 10. J Mol Med (Berl). 2016. PMID: 26452676

3

Tissue-specific changes in the hydroxylysine content and cross-links of collagens and alterations in fibril morphology in lysyl hydroxylase 1 knock-out mice.

Takaluoma K, Hyry M, Lantto J, Sormunen R, Bank RA, Kivirikko KI, Myllyharju J, Soininen R. Takaluoma K, et al. Among authors: sormunen r. J Biol Chem. 2007 Mar 2;282(9):6588-96. doi: 10.1074/jbc.M608830200. Epub 2006 Dec 29. J Biol Chem. 2007. PMID: 17197443 Free article.

4

An endoplasmic reticulum transmembrane prolyl 4-hydroxylase is induced by hypoxia and acts on hypoxia-inducible factor alpha.

Koivunen P, Tiainen P, Hyvärinen J, Williams KE, Sormunen R, Klaus SJ, Kivirikko KI, Myllyharju J. Koivunen P, et al. Among authors: sormunen r. J Biol Chem. 2007 Oct 19;282(42):30544-52. doi: 10.1074/jbc.M704988200. Epub 2007 Aug 27. J Biol Chem. 2007. PMID: 17726031 Free article.

5

Characterization of recombinant human prolyl 3-hydroxylase isoenzyme 2, an enzyme modifying the basement membrane collagen IV.

Tiainen P, Pasanen A, Sormunen R, Myllyharju J. Tiainen P, et al. Among authors: sormunen r. J Biol Chem. 2008 Jul 11;283(28):19432-9. doi: 10.1074/jbc.M802973200. Epub 2008 May 15. J Biol Chem. 2008. PMID: 18487197 Free article.

6

Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.

Hyvärinen J, Hassinen IE, Sormunen R, Mäki JM, Kivirikko KI, Koivunen P, Myllyharju J. Hyvärinen J, et al. Among authors: sormunen r. J Biol Chem. 2010 Apr 30;285(18):13646-57. doi: 10.1074/jbc.M109.084855. Epub 2010 Feb 25. J Biol Chem. 2010. PMID: 20185832 Free PMC article.

7

Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function.

Hyvärinen J, Parikka M, Sormunen R, Rämet M, Tryggvason K, Kivirikko KI, Myllyharju J, Koivunen P. Hyvärinen J, et al. Among authors: sormunen r. J Biol Chem. 2010 Dec 31;285(53):42023-32. doi: 10.1074/jbc.M110.145904. Epub 2010 Oct 15. J Biol Chem. 2010. PMID: 20952382 Free PMC article.

8

Activation of hypoxia response in endothelial cells contributes to ischemic cardioprotection.

Kerkelä R, Karsikas S, Szabo Z, Serpi R, Magga J, Gao E, Alitalo K, Anisimov A, Sormunen R, Pietilä I, Vainio L, Koch WJ, Kivirikko KI, Myllyharju J, Koivunen P. Kerkelä R, et al. Among authors: sormunen r. Mol Cell Biol. 2013 Aug;33(16):3321-9. doi: 10.1128/MCB.00432-13. Epub 2013 Jun 17. Mol Cell Biol. 2013. PMID: 23775121 Free PMC article.

9

Severe Extracellular Matrix Abnormalities and Chondrodysplasia in Mice Lacking Collagen Prolyl 4-Hydroxylase Isoenzyme II in Combination with a Reduced Amount of Isoenzyme I.

Aro E, Salo AM, Khatri R, Finnilä M, Miinalainen I, Sormunen R, Pakkanen O, Holster T, Soininen R, Prein C, Clausen-Schaumann H, Aszódi A, Tuukkanen J, Kivirikko KI, Schipani E, Myllyharju J. Aro E, et al. Among authors: sormunen r. J Biol Chem. 2015 Jul 3;290(27):16964-78. doi: 10.1074/jbc.M115.662635. Epub 2015 May 22. J Biol Chem. 2015. PMID: 26001784 Free PMC article.

10

Loss of assembly of the main basement membrane collagen, type IV, but not fibril-forming collagens and embryonic death in collagen prolyl 4-hydroxylase I null mice.

Holster T, Pakkanen O, Soininen R, Sormunen R, Nokelainen M, Kivirikko KI, Myllyharju J. Holster T, et al. Among authors: sormunen r. J Biol Chem. 2007 Jan 26;282(4):2512-9. doi: 10.1074/jbc.M606608200. Epub 2006 Nov 29. J Biol Chem. 2007. PMID: 17135260 Free article.

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