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Page 1
Essential role for histone deacetylase 11 (HDAC11) in neutrophil biology.
Sahakian E, Chen J, Powers JJ, Chen X, Maharaj K, Deng SL, Achille AN, Lienlaf M, Wang HW, Cheng F, Sodré AL, Distler A, Xing L, Perez-Villarroel P, Wei S, Villagra A, Seto E, Sotomayor EM, Horna P, Pinilla-Ibarz J. Sahakian E, et al. Among authors: sotomayor em. J Leukoc Biol. 2017 Aug;102(2):475-486. doi: 10.1189/jlb.1A0415-176RRR. Epub 2017 May 26. J Leukoc Biol. 2017. PMID: 28550123 Free PMC article.
Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells.
Cheng F, Lienlaf M, Perez-Villarroel P, Wang HW, Lee C, Woan K, Woods D, Knox T, Bergman J, Pinilla-Ibarz J, Kozikowski A, Seto E, Sotomayor EM, Villagra A. Cheng F, et al. Among authors: sotomayor em. Mol Immunol. 2014 Jul;60(1):44-53. doi: 10.1016/j.molimm.2014.02.019. Epub 2014 Apr 18. Mol Immunol. 2014. PMID: 24747960 Free PMC article.
A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs.
Cheng F, Lienlaf M, Wang HW, Perez-Villarroel P, Lee C, Woan K, Rock-Klotz J, Sahakian E, Woods D, Pinilla-Ibarz J, Kalin J, Tao J, Hancock W, Kozikowski A, Seto E, Villagra A, Sotomayor EM. Cheng F, et al. Among authors: sotomayor em. J Immunol. 2014 Sep 15;193(6):2850-62. doi: 10.4049/jimmunol.1302778. Epub 2014 Aug 8. J Immunol. 2014. PMID: 25108026 Free PMC article.
Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function.
Sahakian E, Powers JJ, Chen J, Deng SL, Cheng F, Distler A, Woods DM, Rock-Klotz J, Sodre AL, Youn JI, Woan KV, Villagra A, Gabrilovich D, Sotomayor EM, Pinilla-Ibarz J. Sahakian E, et al. Among authors: sotomayor em. Mol Immunol. 2015 Feb;63(2):579-85. doi: 10.1016/j.molimm.2014.08.002. Epub 2014 Aug 23. Mol Immunol. 2015. PMID: 25155994 Free PMC article.
T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model.
Woods DM, Woan KV, Cheng F, Sodré AL, Wang D, Wu Y, Wang Z, Chen J, Powers J, Pinilla-Ibarz J, Yu Y, Zhang Y, Wu X, Zheng X, Weber J, Hancock WW, Seto E, Villagra A, Yu XZ, Sotomayor EM. Woods DM, et al. Among authors: sotomayor em. Blood. 2017 Jul 13;130(2):146-155. doi: 10.1182/blood-2016-08-731505. Epub 2017 May 26. Blood. 2017. PMID: 28550044 Free PMC article.
Targeting histone deacetylase 6 mediates a dual anti-melanoma effect: Enhanced antitumor immunity and impaired cell proliferation.
Woan KV, Lienlaf M, Perez-Villaroel P, Lee C, Cheng F, Knox T, Woods DM, Barrios K, Powers J, Sahakian E, Wang HW, Canales J, Marante D, Smalley KSM, Bergman J, Seto E, Kozikowski A, Pinilla-Ibarz J, Sarnaik A, Celis E, Weber J, Sotomayor EM, Villagra A. Woan KV, et al. Among authors: sotomayor em. Mol Oncol. 2015 Aug;9(7):1447-1457. doi: 10.1016/j.molonc.2015.04.002. Epub 2015 Apr 24. Mol Oncol. 2015. PMID: 25957812 Free PMC article.
Circumventing immune tolerance through epigenetic modification.
Dubovsky JA, Villagra A, Powers JJ, Wang HW, Pinilla-Ibarz J, Sotomayor EM. Dubovsky JA, et al. Among authors: sotomayor em. Curr Pharm Des. 2010 Jan;16(3):268-76. doi: 10.2174/138161210790170120. Curr Pharm Des. 2010. PMID: 20109136 Review.
136 results